Patient P-03292
Therapy response
Favorable
Tolerance
Deteriorating
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
66%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S14
- Day 101 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 101.
Primary contributors, last 14 days
- Toxicity+22
- Nutritional resilience-14
- GI instability+13
- Inflammatory activity+5
- Treatment adherence-5
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
62%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 84% showed improvement
- median effect visible after 8 days
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 29/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Mucosal barrier integrity ↓50
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 52 and rising
- Autonomic recovery ↓45
- WearableResting HR 82 bpm
- Wearable1,953 steps/day
- Inflammatory signalling ↑40
- BloodInflammatory load index 44
- WearableHRV 31 ms, trending down
DNA
Fictional pharmacogenomic panel
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 2 · butyrate capacity 29/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 34 ms
- Sleep
- 6.7 h
- Steps
- 3,090
- Resting HR
- 79 bpm
Daily log: GI score 52, nutritional resilience 44, adherence 85.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-03218 | 52% | S20 | — | — | 56 |
| P-03120 | 51% | S14 | — | — | 61 |
| P-03221 | 49% | S06 | GI-04 | no change | 64 |
| P-03378 | 48% | S10 | — | — | 59 |
| P-03160 | 46% | S18 | — | — | 63 |
| P-03346 | 46% | S17 | GI-04 | improved | 71 |
| P-03200 | 42% | S16 | — | — | 59 |
| P-03379 | 42% | S12 | GI-04 | improved | 51 |
| P-03405 | 42% | S16 | — | — | 62 |
| P-03027 | 39% | S20 | — | — | 62 |
| P-03031 | 39% | S16 | CR-01 | improved | 49 |
| P-03246 | 38% | S15 | — | — | 61 |