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Patient P-03292

Synthetic patientONX-7 · Day 108 · 25–34 · F · baseline S14Steering view · 3DOpen companion preview
Therapy response
Favorable
Tolerance
Deteriorating
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
66%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 ONX-7 started — Baseline state S14
  2. Day 101 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 101.

Primary contributors, last 14 days
  • Toxicity+22
  • Nutritional resilience-14
  • GI instability+13
  • Inflammatory activity+5
  • Treatment adherence-5

What helped?

No interventions yet.

    LIFE OS recommendation
    GI Support Protocol GI-04
    62%
    probability of meaningful tolerance improvement
    • 284 similar trajectories
    • 84% showed improvement
    • median effect visible after 8 days
    View similar patientsSimulateAdd to intervention cohortAll evidence

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Energy level
    Daily log
    3.7/10
    worsening · -1.2 vs previous 14 d
    Stress level
    Daily log
    6.2/10
    worsening · +1.1 vs previous 14 d
    Pessimism score
    Daily log
    5.5/10
    worsening · +0.9 vs previous 14 d
    Sleep quality
    Wearable
    36.7/100
    worsening · -11.3 vs previous 14 d
    Libido
    Daily log
    3.3/10
    worsening · -0.8 vs previous 14 d
    HRV
    Wearable
    31.4 ms
    worsening · -5.4 vs previous 14 d
    Toxicity
    Blood
    35.6/100
    worsening · +12.6 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 48 from the failing basin, 43 from restoration.

    Would help
    • GI-04 GI Support Protocol
      85% improved among 26 similar · onset 8 d · confidence 59%
    • DT-01 Dosing / Timing Recommendation
      85% improved among 13 similar · onset 5 d · confidence 65%
    • HY-01 Hydration Protocol
      67% improved among 9 similar · onset 4 d · confidence 65%
    • More protein
      GI -4.4 next day on high-intake days · n 26
    Would not help
    • Keep lactose low
      GI +5.5 next day on high-intake days · n 18
    • Keep fat low
      GI +4.2 next day on high-intake days · n 18
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Lactose
      +5.5detractor · 95%
    • Protein
      -4.4supporter · 95%
    • Dietary fat load
      +4.2detractor · 95%
    • Histamine load
      -1no signal · 19%
    • Caffeine
      -0.9no signal · 20%
    • Alcohol
      +0.3no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Butyrate / short-chain fatty acid production ↓80
      • MicrobiomeButyrate capacity 29/100
      • MicrobiomeF. prausnitzii depleted
      • Daily logFibre intake low in recent food logs
    • Mucosal barrier integrity ↓50
      • MicrobiomeAkkermansia low → thinner mucus layer
      • Daily logGI symptom score 52 and rising
    • Autonomic recovery ↓45
      • WearableResting HR 82 bpm
      • Wearable1,953 steps/day
    • Inflammatory signalling ↑40
      • BloodInflammatory load index 44
      • WearableHRV 31 ms, trending down
    DNA
    Fictional pharmacogenomic panel
    • CYP2D6 Normal metabolizer
      Expected exposure
    Microbiome
    Shannon diversity 2 · butyrate capacity 29/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisNormal
    • Bifidobacterium longumLow
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    34 ms
    Sleep
    6.7 h
    Steps
    3,090
    Resting HR
    79 bpm
    Daily log: GI score 52, nutritional resilience 44, adherence 85.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
    • Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Track each bowel movement today: time, stool form, urgency, overnight waking
    • A 15-minute walk after lunch
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • Electrolyte solution, one sachet after any loose stool
    • Fictional demo item: oral nutrition supplement with lunch

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0321852%S20——56
    P-0312051%S14——61
    P-0322149%S06GI-04no change64
    P-0337848%S10——59
    P-0316046%S18——63
    P-0334646%S17GI-04improved71
    P-0320042%S16——59
    P-0337942%S12GI-04improved51
    P-0340542%S16——62
    P-0302739%S20——62
    P-0303139%S16CR-01improved49
    P-0324638%S15——61