Patient P-03441

Synthetic patientONX-7 · Day 114 · 25–34 · M · baseline S19Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Improving

GI state

Favorable

Inflammatory state

Favorable

Nutritional resilience

Improving

Discontinuation risk

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 ONX-7 started — Baseline state S19
Day 90 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 90 AD-05 recommended — Adherence Support AD-05
Day 91 Patient accepted — Started AD-05 in the companion
Day 96 GI symptom burden −12% vs expected — Adherence Support AD-05
Day 102 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 90.

Primary contributors, last 14 days

Toxicity-8
Nutritional resilience+7
Treatment adherence-5

What helped?

Adherence Support AD-05Day 90
Result: symptom burden −12%

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Energy level

Daily log

6.7/10

improving · +0.3 vs previous 14 d

Stress level

Daily log

2.6/10

improving · -0.6 vs previous 14 d

Pessimism score

Daily log

4.4/10

improving · -0.3 vs previous 14 d

Sleep quality

Wearable

56.2/100

stable · +0.6 vs previous 14 d

Libido

Daily log

5.6/10

improving · +0.2 vs previous 14 d

HRV

Wearable

65.6 ms

stable · +0.6 vs previous 14 d

Toxicity

Blood

8.9/100

improving · -2.5 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 75 from the failing basin, 41 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.
More protein
GI -4.4 next day on high-intake days · n 23

Would not help

AD-05 Adherence Support
already tried, no meaningful change
Keep lactose low
GI +5.2 next day on high-intake days · n 19

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Lactose
+5.2detractor · 95%
Protein
-4.4supporter · 95%
Caffeine
-1.3no signal · 28%
Alcohol
-1.2no signal · 27%
Histamine load
+0.7no signal · 18%
Dietary fat load
+0.5no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Inflammatory signalling ↓45
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer

DNA

Fictional pharmacogenomic panel

IL6 -174 G/C
Higher inflammatory tone
CYP2D6 Normal metabolizer
Expected exposure

Microbiome

Shannon diversity 4.6 · butyrate capacity 54/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 66 ms
Sleep: 6.8 h
Steps: 4,221
Resting HR: 61 bpm

Daily log: GI score 14, nutritional resilience 72, adherence 90.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
A 15-minute walk after lunch
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-03308	45%	S04	BR-03	improved	39
P-03475	40%	S20	HY-01	improved	50
P-03373	38%	S17	BR-03	improved	34
P-03380	38%	S16	AD-05	improved	34
P-03204	37%	S16	AD-05	improved	48
P-03143	36%	S11	DT-01	improved	49
P-03114	35%	S11	DT-01	improved	48
P-03193	34%	S13	DT-01	improved	53
P-03375	34%	S09	DT-01	improved	52
P-03408	34%	S09	HY-01	improved	53
P-03208	33%	S02	BR-03	improved	57
P-03424	33%	S12	AD-05	improved	41