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Patient P-03471

Synthetic patientONX-7 · Day 95 · 65–74 · M · baseline S08Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Deteriorating
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
34%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 ONX-7 started — Baseline state S08
  2. Day 11 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 11.

Primary contributors, last 14 days
  • Toxicity+17
  • Inflammatory activity+9
  • Nutritional resilience-9
  • GI instability+6
  • Treatment adherence-5

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Energy level
    Daily log
    4.4/10
    worsening · -0.5 vs previous 14 d
    Stress level
    Daily log
    6.1/10
    worsening · +0.7 vs previous 14 d
    Pessimism score
    Daily log
    5.5/10
    worsening · +0.8 vs previous 14 d
    Sleep quality
    Wearable
    13.5/100
    worsening · -4.1 vs previous 14 d
    Libido
    Daily log
    3.6/10
    stable · -0.2 vs previous 14 d
    HRV
    Wearable
    26.2 ms
    worsening · -2.3 vs previous 14 d
    Toxicity
    Blood
    27.8/100
    worsening · +1.0 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 55 from the failing basin, 33 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    • More protein
      GI -7.3 next day on high-intake days · n 26
    Would not help
    • AD-05 Adherence Support
      only 25% improved among 12 similar
    • Keep fat low
      GI +6.7 next day on high-intake days · n 19
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Protein
      -7.3supporter · 95%
    • Dietary fat load
      +6.7detractor · 95%
    • Histamine load
      -2.6no signal · 41%
    • Lactose
      +2.2no signal · 37%
    • Caffeine
      +0.6no signal · 15%
    • Alcohol
      -0.3no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Autonomic recovery ↓65
      • WearableResting HR 78 bpm
      • Wearable2,309 steps/day
      • WearableShort sleep window
    • Butyrate / short-chain fatty acid production ↓60
      • MicrobiomeButyrate capacity 38/100
      • MicrobiomeF. prausnitzii depleted
    • Mucosal barrier integrity ↓40
      • MicrobiomeAkkermansia low → thinner mucus layer
      • WearableSleep 5.1 h, below personal baseline
    • Drug metabolism and exposure ↑35
      • DNADPYD *2A → slower clearance
    • Inflammatory signalling ↑15
      • WearableHRV 26 ms, trending down
    DNA
    Fictional pharmacogenomic panel
    • DPYD *2A heterozygous
      Slower drug clearance
    • CYP2D6 Normal metabolizer
      Expected exposure
    Microbiome
    Shannon diversity 2.6 · butyrate capacity 38/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisNormal
    • Bifidobacterium longumNormal
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    28 ms
    Sleep
    5.9 h
    Steps
    4,450
    Resting HR
    73 bpm
    Daily log: GI score 34, nutritional resilience 53, adherence 91.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • A 15-minute walk after lunch
    • Protect a 7.5-hour sleep window; screens off 30 minutes before
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0325550%S01HY-01improved53
    P-0342049%S08——59
    P-0348448%S07DT-01improved49
    P-0317945%S05GI-04improved52
    P-0332843%S15GI-04improved59
    P-0338943%S01——50
    P-0319842%S11——52
    P-0314441%S16HY-01improved52
    P-0317140%S10——55
    P-0317240%S17DT-01no change48
    P-0318540%S04——65
    P-0321440%S18——68