Patient P-02029
Synthetic patientMETA-24 · Day 177 · 45–54 · F · baseline S18Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Improving
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
52%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S18
- Day 21 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 21.
Primary contributors, last 14 days
- Toxicity-14
- Inflammatory activity-8
- Treatment adherence+8
- Nutritional resilience-6
- GI instability-2
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
65%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 88% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable61 min
stable · +1.1 vs previous 14 d
Sleep duration
Wearable6.2 h
stable · +0.1 vs previous 14 d
Energy level
Daily log2.7/10
improving · +0.3 vs previous 14 d
Steps
Wearable7,616
stable · +287 vs previous 14 d
GI burden
Companion58.7/100
stable · +0.9 vs previous 14 d
Adherence
Companion71.9 %
stable · -0.5 vs previous 14 d
Sleep quality
Wearable23/100
improving · +1.3 vs previous 14 d
Glucose, CGM daily mean
CGM144 mg/dL
stable · -0.9 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading towards restoration · 35 from the failing basin, 59 from restoration.
Good elements to keep
- Protein (supports)perturbation · steering +11.8
- Proteinsupporter · GI -6.3 next day
Main detractors to watch
- Low butyrate capacityhidden · steering -17.5
- FUT2 non-secretorhidden · steering -10.6
- Dietary fat loadperturbation · steering -9.2
- Histamine loadperturbation · steering -8.9
- Histamine loaddetractor · GI +5.2 next day
- Ultra-processed fooddetractor · GI +5 next day
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-6.3supporter · 95%
- Histamine load+5.2detractor · 95%
- Ultra-processed food+5detractor · 95%
- Dietary fat load+4.9detractor · 95%
- Simple carbohydrates+3.9detractor · 90%
- Insoluble fibre-2.4no signal · 46%
- Caffeine+0.3no signal · 15%
- Alcohol+0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓80
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 59 and rising
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 29/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↓65
- DNAIL6 -174 variant raises baseline inflammatory tone
- BloodInflammatory load index 59
- WearableHRV 32 ms, trending down
- Autonomic recovery ↑45
- WearableResting HR 79 bpm
- WearableShort sleep window
- Drug metabolism and exposure ↑20
- BloodToxicity index 46
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
- GLP1R rs6923761 AAltered receptor sensitivity
Microbiome
Shannon diversity 2.6 · butyrate capacity 29/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 29 ms
- Sleep
- 6.3 h
- Steps
- 7,617
- Resting HR
- 79 bpm
Daily log: GI score 59, nutritional resilience 33, adherence 72.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.