Patient P-02223

Synthetic patientMETA-24 · Day 178 · 55–64 · M · baseline S20Steering view · 3D Open companion preview

Therapy response

Stable

Tolerance

Favorable

GI state

Improving

Inflammatory state

Improving

Nutritional resilience

Improving

Discontinuation risk

13%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S20
Day 14 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 22 HY-01 recommended — Hydration Protocol HY-01
Day 23 Patient accepted — Started HY-01 in the companion
Day 27 GI symptom burden −14% vs expected — Hydration Protocol HY-01
Day 33 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 14.

Primary contributors, last 14 days

GI instability-13
Inflammatory activity-13
Nutritional resilience+6
Treatment adherence-3
Toxicity-2

What helped?

Hydration Protocol HY-01Day 22
Result: symptom burden −14%

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

53 min

stable · -1.4 vs previous 14 d

Sleep duration

Wearable

6.7 h

stable · -0.1 vs previous 14 d

Energy level

Daily log

5.1/10

stable · +0.0 vs previous 14 d

Steps

Wearable

5,446

stable · +14 vs previous 14 d

GI burden

Companion

24.4/100

improving · -3.3 vs previous 14 d

Adherence

Companion

97.3 %

stable · +0.4 vs previous 14 d

Sleep quality

Wearable

44.8/100

stable · +0.4 vs previous 14 d

Glucose, CGM daily mean

CGM

135 mg/dL

stable · +1.4 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 64 from the failing basin, 31 from restoration.

Good elements to keep

Protein (supports)
perturbation · steering +10.9
Hydration Protocol HY-01
intervention · steering +9.2
Daily walks resumed
perturbation · steering +3.3
Protein
supporter · GI -5.7 next day

Main detractors to watch

Low butyrate capacity
hidden · steering -17.5
Dietary fat load
perturbation · steering -8.7
Low microbial diversity
hidden · steering -7.7
Bacteroides fragilis elevated
hidden · steering -7.4
Dietary fat load
detractor · GI +4.6 next day
Ultra-processed food
detractor · GI +4.1 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Protein
-5.7supporter · 95%
Dietary fat load
+4.6detractor · 95%
Ultra-processed food
+4.1detractor · 92%
Simple carbohydrates
+4detractor · 74%
Caffeine
+0.9no signal · 17%
Histamine load
-0.7no signal · 15%
Alcohol
-0.7no signal · 15%
Insoluble fibre
+0.2no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Butyrate / short-chain fatty acid production ↓60
- MicrobiomeButyrate capacity 44/100
- MicrobiomeF. prausnitzii depleted
Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion

DNA

Fictional pharmacogenomic panel

CYP2D6 Normal metabolizer
Expected exposure

Microbiome

Shannon diversity 2.6 · butyrate capacity 44/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiLow
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 48 ms
Sleep: 6.5 h
Steps: 5,808
Resting HR: 59 bpm

Daily log: GI score 24, nutritional resilience 60, adherence 97.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02033	48%	S06	GI-04	improved	51
P-02339	48%	S03	DT-01	improved	50
P-02538	47%	S02	GI-04	improved	59
P-02303	46%	S15	GI-04	improved	48
P-02395	46%	S12	DT-01	improved	57
P-02037	45%	S04	GI-04	improved	53
P-02455	45%	S09	DT-01	improved	50
P-02235	44%	S14	DT-01	improved	50
P-02479	44%	S13	DT-01	improved	48
P-02645	44%	S02	HY-01	improved	56
P-02126	43%	S16	DT-01	improved	59
P-02274	43%	S15	DT-01	improved	50