Patient P-02241
Therapy response
Improving
Tolerance
Stable
GI state
Improving
Inflammatory state
Stable
Nutritional resilience
Improving
Discontinuation risk
56%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S09
- Day 66 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 77 GI-04 recommended — GI Support Protocol GI-04
- Day 78 Patient accepted — Started GI-04 in the companion
- Day 79 ME-01 recommended — Monitoring Escalation ME-01
- Day 80 Patient accepted — Started ME-01 in the companion
- Day 83 Deterioration detected before clinical escalation — Monitoring Escalation ME-01
- Day 86 GI symptom burden −40% vs expected — GI Support Protocol GI-04
- Day 92 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 66.
Primary contributors, last 14 days
- Treatment adherence-6
- GI instability-5
- Nutritional resilience+5
- Inflammatory activity+3
What helped?
- GI Support Protocol GI-04Day 77Result: symptom burden −40%
- Monitoring Escalation ME-01Day 79Result: deterioration detected before clinical escalation
LIFE OS recommendation
Dietary Support Protocol NP-02
54%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 64% showed improvement
- median effect visible after 10 days
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓80
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 49 and rising
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 22/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↑60
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 52
- WearableHRV 28 ms, trending down
- Drug metabolism and exposure ↑60
- DNACYP2D6 poor metabolizer → higher exposure
- BloodToxicity index 44
- Autonomic recovery ↑25
- WearableResting HR 76 bpm
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Poor metabolizerHigher exposure at standard dose
Microbiome
Shannon diversity 3 · butyrate capacity 22/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 33 ms
- Sleep
- 7.1 h
- Steps
- 5,722
- Resting HR
- 74 bpm
Daily log: GI score 49, nutritional resilience 46, adherence 44.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02048 | 21% | S02 | — | — | 77 |
| P-02115 | 23% | S14 | GI-04 | improved | 75 |
| P-02575 | 23% | S14 | ME-01 | improved | 73 |
| P-02550 | 23% | S01 | — | — | 70 |
| P-02192 | 22% | S05 | — | — | 69 |
| P-02659 | 26% | S09 | — | — | 69 |
| P-02214 | 21% | S08 | SC-12 | no change | 69 |
| P-02356 | 22% | S08 | — | — | 69 |
| P-02083 | 21% | S13 | — | — | 69 |
| P-02293 | 22% | S15 | HY-01 | no change | 68 |
| P-02591 | 36% | S13 | — | — | 68 |
| P-02090 | 22% | S04 | — | — | 68 |