Patient P-02459
Synthetic patientMETA-24 · Day 127 · 55–64 · M · baseline S05Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Improving
GI state
Deteriorating
Inflammatory state
Favorable
Nutritional resilience
Declining
Discontinuation risk
49%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S05
- Day 14 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 22 HY-01 recommended — Hydration Protocol HY-01
- Day 23 Patient accepted — Started HY-01 in the companion
- Day 27 GI symptom burden −28% vs expected — Hydration Protocol HY-01
- Day 33 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 14.
Primary contributors, last 14 days
- GI instability+21
- Toxicity-14
- Nutritional resilience-8
- Treatment adherence-4
- Inflammatory activity-3
What helped?
- Hydration Protocol HY-01Day 22Result: symptom burden −28%
LIFE OS recommendation
Dosing / Timing Recommendation DT-01
57%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 75% showed improvement
- median effect visible after 5 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable20 min
worsening · -3.8 vs previous 14 d
Sleep duration
Wearable7 h
stable · -0.2 vs previous 14 d
Energy level
Daily log5.5/10
stable · +0.1 vs previous 14 d
Steps
Wearable3,077
stable · -128 vs previous 14 d
GI burden
Companion38.5/100
stable · +0.2 vs previous 14 d
Adherence
Companion91.7 %
stable · +1.5 vs previous 14 d
Sleep quality
Wearable42.3/100
worsening · -3.1 vs previous 14 d
Glucose, CGM daily mean
CGM128 mg/dL
stable · +1.4 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 56 from the failing basin, 34 from restoration.
Would help
- DT-01 Dosing / Timing Recommendation75% improved among 16 similar · onset 5 d · confidence 60%
- More proteinGI -7.1 next day on high-intake days · n 21
Would not help
- Keep simple carbs lowGI +5.8 next day on high-intake days · n 19
- Keep alcohol lowGI +5.7 next day on high-intake days · n 15
- Keep fat lowGI +5.6 next day on high-intake days · n 22
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-7.1supporter · 95%
- Simple carbohydrates+5.8detractor · 95%
- Alcohol+5.7detractor · 95%
- Dietary fat load+5.6detractor · 95%
- Ultra-processed food+4.2detractor · 94%
- Histamine load+1.2no signal · 29%
- Insoluble fibre-1.2no signal · 20%
- Caffeine+1no signal · 16%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓35
- MicrobiomeButyrate capacity 34/100
- Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
- Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion
- Autonomic recovery ↓20
- Wearable3,077 steps/day
DNA
Fictional pharmacogenomic panel
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 1.9 · butyrate capacity 34/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 48 ms
- Sleep
- 7.2 h
- Steps
- 3,332
- Resting HR
- 56 bpm
Daily log: GI score 39, nutritional resilience 58, adherence 92.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.