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Patient P-02459

Synthetic patientMETA-24 · Day 127 · 55–64 · M · baseline S05Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Improving
GI state
Deteriorating
Inflammatory state
Favorable
Nutritional resilience
Declining
Discontinuation risk
49%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 started — Baseline state S05
  2. Day 14 Trajectory diverged from prediction — Observed response fell below the model's expected path.
  3. Day 22 HY-01 recommended — Hydration Protocol HY-01
  4. Day 23 Patient accepted — Started HY-01 in the companion
  5. Day 27 GI symptom burden −28% vs expected — Hydration Protocol HY-01
  6. Day 33 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 14.

Primary contributors, last 14 days
  • GI instability+21
  • Toxicity-14
  • Nutritional resilience-8
  • Treatment adherence-4
  • Inflammatory activity-3

What helped?

  • Hydration Protocol HY-01Day 22
    Result: symptom burden −28%
LIFE OS recommendation
Dosing / Timing Recommendation DT-01
57%
probability of meaningful tolerance improvement
  • 284 similar trajectories
  • 75% showed improvement
  • median effect visible after 5 days
View similar patientsSimulateAdd to intervention cohortAll evidence

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes
Wearable
20 min
worsening · -3.8 vs previous 14 d
Sleep duration
Wearable
7 h
stable · -0.2 vs previous 14 d
Energy level
Daily log
5.5/10
stable · +0.1 vs previous 14 d
Steps
Wearable
3,077
stable · -128 vs previous 14 d
GI burden
Companion
38.5/100
stable · +0.2 vs previous 14 d
Adherence
Companion
91.7 %
stable · +1.5 vs previous 14 d
Sleep quality
Wearable
42.3/100
worsening · -3.1 vs previous 14 d
Glucose, CGM daily mean
CGM
128 mg/dL
stable · +1.4 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →

Heading towards failing · 56 from the failing basin, 34 from restoration.

Would help
  • DT-01 Dosing / Timing Recommendation
    75% improved among 16 similar · onset 5 d · confidence 60%
  • More protein
    GI -7.1 next day on high-intake days · n 21
Would not help
  • Keep simple carbs low
    GI +5.8 next day on high-intake days · n 19
  • Keep alcohol low
    GI +5.7 next day on high-intake days · n 15
  • Keep fat low
    GI +5.6 next day on high-intake days · n 22
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Protein
    -7.1supporter · 95%
  • Simple carbohydrates
    +5.8detractor · 95%
  • Alcohol
    +5.7detractor · 95%
  • Dietary fat load
    +5.6detractor · 95%
  • Ultra-processed food
    +4.2detractor · 94%
  • Histamine load
    +1.2no signal · 29%
  • Insoluble fibre
    -1.2no signal · 20%
  • Caffeine
    +1no signal · 16%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Butyrate / short-chain fatty acid production ↓35
    • MicrobiomeButyrate capacity 34/100
  • Mucosal barrier integrity ↓30
    • MicrobiomeAkkermansia low → thinner mucus layer
  • Inflammatory signalling ↓20
    • MicrobiomeBacteroides fragilis expansion
  • Autonomic recovery ↓20
    • Wearable3,077 steps/day
DNA
Fictional pharmacogenomic panel
  • CYP2D6 Normal metabolizer
    Expected exposure
Microbiome
Shannon diversity 1.9 · butyrate capacity 34/100
  • Akkermansia muciniphilaLow
  • Faecalibacterium prausnitziiNormal
  • Bacteroides fragilisHigh
  • Bifidobacterium longumLow
  • EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
HRV
48 ms
Sleep
7.2 h
Steps
3,332
Resting HR
56 bpm
Daily log: GI score 39, nutritional resilience 58, adherence 92.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Keep meals regular; three to four moderate portions spaced through the day
  • Include a cooked vegetable portion with each main meal
  • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
  • Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
  • Log the daily check-in; one line is enough
  • A 15-minute walk after lunch
  • Keep the sleep window steady
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the dose at the same time relative to your evening meal
  • No additional supplements this week
  • Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
PatientSimilarityBaselineInterventionOutcomeResponse today
P-0235146%S16——51
P-0230545%S20——46
P-0205344%S03——54
P-0212844%S07——57
P-0221944%S13——60
P-0248544%S05HY-01improved63
P-0253844%S02GI-04improved59
P-0262244%S07——50
P-0209143%S07——57
P-0215043%S11HY-01improved45
P-0222343%S20HY-01improved49
P-0233943%S03DT-01improved50