Patients needing attention
eligible for AD-05 · confidence ≥ 70%: 19 patients, mean day 140. 21% have deteriorating tolerance, 68% unstable GI, 100% carry ≥60% discontinuation risk; mean GI 66, adherence 48%. Dominant clusters: EC-03 84%, LT 16%.
Shared biology: FUT2 non-secretor 84%, Cluster EC-03 (high response / high intolerance) 84%, Adherence < 60% 84%, Low microbial diversity 79%, Baseline state S14 74%, Low butyrate capacity 63%, IL6 high-expression variant 58%. Dietary detractors: fat in 95%, histamine in 84%, lactose in 74%.
What worked: GI-04 improved 60% of 5; what did not: SC-12 improved only 40% of 5. By biology: GI-04 works best in Cluster EC-03 (high response / high intolerance) (60%) and worst in FUT2 non-secretor (50%); SC-12 works best in FUT2 non-secretor (50%) and worst in Low microbial diversity (40%).
No learned rules apply yet; run learning after the first campaign results.
| Patient | Day | Baseline | GI | Tolerance | GI score | Discontinuation | Cluster |
|---|---|---|---|---|---|---|---|
| P-03067 | 150 | S14 | Unstable | Deteriorating | 72 | 96% | EC-03 |
| P-03078 | 139 | S14 | Unstable | Unstable | 71 | 96% | EC-03 |
| P-03177 | 140 | S10 | Unstable | Stable | 81 | 96% | LT |
| P-03375 | 139 | S14 | Unstable | Deteriorating | 71 | 96% | EC-03 |
| P-03427 | 107 | S14 | Unstable | Favorable | 68 | 96% | EC-03 |
| P-03488 | 146 | S14 | Unstable | Improving | 76 | 96% | EC-03 |
| P-03345 | 140 | S14 | Unstable | Stable | 69 | 95% | EC-03 |
| P-03230 | 149 | S09 | Unstable | Improving | 73 | 94% | EC-03 |
| P-03058 | 140 | S14 | Unstable | Stable | 67 | 93% | EC-03 |
| P-03459 | 145 | S14 | Improving | Improving | 56 | 88% | EC-03 |
| P-03034 | 138 | S14 | Unstable | Stable | 78 | 85% | EC-03 |
| P-03405 | 116 | S14 | Improving | Improving | 58 | 84% | EC-03 |
| P-03500 | 139 | S14 | Stable | Improving | 52 | 81% | EC-03 |
| P-03153 | 143 | S08 | Unstable | Deteriorating | 67 | 80% | LT |
| P-03419 | 146 | S14 | Improving | Favorable | 50 | 78% | EC-03 |
| P-03109 | 143 | S03 | Deteriorating | Deteriorating | 58 | 76% | EC-03 |
| P-03253 | 147 | S15 | Unstable | Stable | 69 | 75% | LT |
| P-03361 | 150 | S14 | Unstable | Improving | 63 | 75% | EC-03 |
| P-03124 | 138 | S14 | Improving | Stable | 49 | 64% | EC-03 |