DeepGene damage signature
SyntheticSynthetic demo data2 samples: baseline day 0 · retest day 90
Damage score · retest day 90
13/100
vs baseline (day 0)
-27
8 improved · 1 worsened
synthetic signature · consistent with this patient's biology
- 1 opportunist above range: Clostridioides difficile
- 1 keystone species absent
- 5 resistance genes
Pathogens / opportunists1/5
↓ from 3
Keystone species1/8
↓ from 2
Diversity0/2
↓ from 1
Metabolic modules0/4
Vitamin synthesis1/7
↓ from 2
Oral translocation0/1
↓ from 1
Host DNA0/1
Tissue recycling0/1
Central mechanisms0/2
Virulence factors1/1
↓ from 2
Antibiotic resistance genes5/5
Genetic predisposition2/2
Opportunists above range
Clostridioides difficile 0.809% AR
Keystone species absent
Akkermansia muciniphila
Capacity
Shannon 3.42 · butyrate 776 CPM · SCFA 1276
1 vitamins below
Host & mechanisms
tissue recycling 25/100
oral translocation 1.87% AR
5 resistance genes · 1 virulence factors
Import a sample
A baseline sample re-initializes this patient's microbiome, pathways and predispositions from the measurement; a retest adds a comparison and updates them. Every theory, steering gain and dietary sensitivity downstream is then conditioned on the measured signature.
All elements · baseline → latest
Value, status vs the expected range, and the implication on health. Changes coloured: green improved / resolved, red worsened / new.
Pathogens / opportunists · 5
| Escherichia coli | 0.774 % AR · in range | 0.747 % AR · in range | expected <= 1% | In excess raises LPS load and zonulin release, opening tight junctions. |
| Klebsiella pneumoniae | 3.839 % AR · above range | 0.16 % AR · in range(improved) | expected <= 0.3% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Enterococcus faecium | 6.399 % AR · above range | 0.029 % AR · in range(improved) | expected <= 0.5% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Streptococcus gallolyticus | 1.28 % AR · above range | 0.055 % AR · in range(improved) | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Clostridioides difficile | 0.019 % AR · in range | 0.809 % AR · above range(worsened) | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
Keystone species · 8
| Akkermansia muciniphila | 0 % AR · absent | 0 % AR · absent | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Bifidobacterium longum | 0 % AR · absent | 0.49 % AR · in range(improved) | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Butyricicoccus pullicaecorum | 0.75 % AR · in range | 0.22 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Eubacterium rectale | 0.39 % AR · in range | 0.33 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Faecalibacterium prausnitzii | 0.39 % AR · in range | 0.63 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Lactobacillus species | 0.56 % AR · in range | 0.89 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Roseburia intestinalis | 0.8 % AR · in range | 0.12 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Ruminococcus bromii | 0.74 % AR · in range | 0.56 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
Diversity · 2
| indice Shannon | 2.99 · below range | 3.42 · in range(improved) | expected >= 3.0 | Low diversity: fewer reserve metabolic routes, slower recovery after perturbation. |
| numar de specii detectate | 132 specii · in range | 140 specii · in range | expected >= 100 | Species count below reference. |
Metabolic modules · 4
| Butyrate production | 713 CPM · in range | 776 CPM · in range | expected 255.83-1089.91 CPM | Butyrate is the main colonocyte fuel and barrier signal. |
| Short Chain Fatty Acid Production | 1104 CPM · in range | 1276 CPM · in range | expected 535.03-1572.59 CPM | Total SCFA capacity. |
| GABA production | 389 CPM · in range | 463 CPM · in range | expected 87.31-766.53 CPM | Gut–brain axis capacity. |
| H2S production (sulfate reduction) | 117 CPM · in range | 139 CPM · in range | expected banda de referinta | Hydrogen sulfide above band irritates the mucosa. |
Vitamin synthesis · 7
| Vitamin B1 - Thiamin | 390 CPM · below range | 246 CPM · below range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B2 - Riboflavin | 533 CPM · below range | 3579 CPM · in range(improved) | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B5 - Pantothenic acid | 4185 CPM · in range | 2956 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B6 - Pyridoxine | 3500 CPM · in range | 3799 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B7 - Biotin | 3045 CPM · in range | 4485 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B9 - Folate | 3582 CPM · in range | 3377 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B12 - Cobalamin | 3609 CPM · in range | 2525 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
Oral translocation · 1
| Translocare orala (indice) | 2.93 % AR · above range | 1.87 % AR · in range(improved) | expected <= 2% | Oral taxa in stool: reduced gastric barrier or dysbiosis. |
Host DNA · 1
| fragmentare mixta | 162 pb · in range | 156 pb · in range | expected 150-170 pb | Host cell-free DNA fragmentation pattern. |
Tissue recycling · 1
| indice de reciclare tisulara | 34 /100 · in range | 25 /100 · in range | expected < 35 | Epithelial turnover. |
Central mechanisms · 2
| molecular_mimicry | 55 /100 · in range | 53 /100 · in range | expected < 65 | Cross-reactive antigen load. |
| estrobolome | 54 /100 · in range | 54 /100 · in range | expected < 65 | Estrogen-recycling capacity. |
Virulence factors · 2
| fimD outer membrane usher | 83 potriviri/M · present | 37 potriviri/M · present | expected absent | Virulence factor detected. |
| chuA heme/hemoglobin receptor | 85 potriviri/M · present | resolved(resolved) | expected absent | Virulence factor detected. |
Antibiotic resistance genes · 5
| sul1 | 8.9 citiri/M · present | 10.3 citiri/M · present | expected nedetectat | Resistance gene detected. |
| sul2 | 7.4 citiri/M · present | 9.2 citiri/M · present | expected nedetectat | Resistance gene detected. |
| tet(O/M/O) | 2.6 citiri/M · present | 4.1 citiri/M · present | expected nedetectat | Resistance gene detected. |
| Ecol_ampC_BLA | 7.6 citiri/M · present | 8.8 citiri/M · present | expected nedetectat | Resistance gene detected. |
| aadA | 3.1 citiri/M · present | 2 citiri/M · present | expected nedetectat | Resistance gene detected. |
Genetic predisposition · 2
| FUT2 | 2.27 OR · risk variant | 3.3 OR · risk variant | expected reference genotype | Reduced mucosal fucosylation |
| IL6 | 3.03 OR · risk variant | 1.62 OR · risk variant | expected reference genotype | Higher inflammatory tone |