DeepGene damage signature
SyntheticSynthetic demo data2 samples: baseline day 0 · retest day 90
Damage score · retest day 90
29/100
vs baseline (day 0)
+13
1 improved · 6 worsened
synthetic signature · consistent with this patient's biology
- 3 opportunists above range: Klebsiella pneumoniae, Enterococcus faecium, Streptococcus gallolyticus
- 1 keystone species absent
- 5 resistance genes
Pathogens / opportunists3/5
↑ from 2
Keystone species1/8
Diversity0/2
Metabolic modules0/4
Vitamin synthesis1/7
Oral translocation1/1
↑ from 0
Host DNA0/1
Tissue recycling0/1
Central mechanisms0/2
Virulence factors1/1
Antibiotic resistance genes5/5
↑ from 2
Genetic predisposition2/2
Opportunists above range
Enterococcus faecium 4.713% AR
Klebsiella pneumoniae 2.828% AR
Streptococcus gallolyticus 0.943% AR
Keystone species absent
Akkermansia muciniphila
Capacity
Shannon 3.04 · butyrate 770 CPM · SCFA 1222
1 vitamins below
Host & mechanisms
tissue recycling 27/100
oral translocation 2.17% AR
5 resistance genes · 1 virulence factors
Import a sample
A baseline sample re-initializes this patient's microbiome, pathways and predispositions from the measurement; a retest adds a comparison and updates them. Every theory, steering gain and dietary sensitivity downstream is then conditioned on the measured signature.
All elements · baseline → latest
Value, status vs the expected range, and the implication on health. Changes coloured: green improved / resolved, red worsened / new.
Pathogens / opportunists · 5
| Escherichia coli | 0.367 % AR · in range | 0.341 % AR · in range | expected <= 1% | In excess raises LPS load and zonulin release, opening tight junctions. |
| Klebsiella pneumoniae | 0.185 % AR · in range | 2.828 % AR · above range(worsened) | expected <= 0.3% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Enterococcus faecium | 3.191 % AR · above range | 4.713 % AR · above range | expected <= 0.5% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Streptococcus gallolyticus | 0.036 % AR · in range | 0.943 % AR · above range(worsened) | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Clostridioides difficile | 0.638 % AR · above range | 0.059 % AR · in range(improved) | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
Keystone species · 8
| Akkermansia muciniphila | 0 % AR · absent | 0 % AR · absent | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Bifidobacterium longum | 1.18 % AR · in range | 0.37 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Butyricicoccus pullicaecorum | 0.06 % AR · in range | 1.15 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Eubacterium rectale | 0.39 % AR · in range | 0.16 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Faecalibacterium prausnitzii | 0.14 % AR · in range | 0.06 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Lactobacillus species | 1.29 % AR · in range | 1.16 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Roseburia intestinalis | 0.65 % AR · in range | 1.18 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Ruminococcus bromii | 0.45 % AR · in range | 0.67 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
Diversity · 2
| indice Shannon | 3.49 · in range | 3.04 · in range | expected >= 3.0 | Low diversity: fewer reserve metabolic routes, slower recovery after perturbation. |
| numar de specii detectate | 145 specii · in range | 143 specii · in range | expected >= 100 | Species count below reference. |
Metabolic modules · 4
| Butyrate production | 836 CPM · in range | 770 CPM · in range | expected 255.83-1089.91 CPM | Butyrate is the main colonocyte fuel and barrier signal. |
| Short Chain Fatty Acid Production | 1329 CPM · in range | 1222 CPM · in range | expected 535.03-1572.59 CPM | Total SCFA capacity. |
| GABA production | 473 CPM · in range | 413 CPM · in range | expected 87.31-766.53 CPM | Gut–brain axis capacity. |
| H2S production (sulfate reduction) | 124 CPM · in range | 129 CPM · in range | expected banda de referinta | Hydrogen sulfide above band irritates the mucosa. |
Vitamin synthesis · 7
| Vitamin B1 - Thiamin | 357 CPM · below range | 260 CPM · below range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B2 - Riboflavin | 2712 CPM · in range | 3800 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B5 - Pantothenic acid | 3331 CPM · in range | 4192 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B6 - Pyridoxine | 3205 CPM · in range | 3865 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B7 - Biotin | 4456 CPM · in range | 2580 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B9 - Folate | 3735 CPM · in range | 2646 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B12 - Cobalamin | 2676 CPM · in range | 4108 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
Oral translocation · 1
| Translocare orala (indice) | 1.49 % AR · in range | 2.17 % AR · above range(worsened) | expected <= 2% | Oral taxa in stool: reduced gastric barrier or dysbiosis. |
Host DNA · 1
| fragmentare mixta | 166 pb · in range | 162 pb · in range | expected 150-170 pb | Host cell-free DNA fragmentation pattern. |
Tissue recycling · 1
| indice de reciclare tisulara | 22 /100 · in range | 27 /100 · in range | expected < 35 | Epithelial turnover. |
Central mechanisms · 2
| molecular_mimicry | 49 /100 · in range | 58 /100 · in range | expected < 65 | Cross-reactive antigen load. |
| estrobolome | 49 /100 · in range | 52 /100 · in range | expected < 65 | Estrogen-recycling capacity. |
Virulence factors · 1
| fimD outer membrane usher | 56 potriviri/M · present | 99 potriviri/M · present | expected absent | Virulence factor detected. |
Antibiotic resistance genes · 5
| sul1 | 9 citiri/M · present | 10.2 citiri/M · present | expected nedetectat | Resistance gene detected. |
| sul2 | 1.9 citiri/M · present | 7.2 citiri/M · present | expected nedetectat | Resistance gene detected. |
| tet(O/M/O) | — | 4.6 citiri/M · present(new) | expected nedetectat | Resistance gene detected. |
| Ecol_ampC_BLA | — | 1.7 citiri/M · present(new) | expected nedetectat | Resistance gene detected. |
| aadA | — | 4.7 citiri/M · present(new) | expected nedetectat | Resistance gene detected. |
Genetic predisposition · 2
| CYP2D6 | 3.18 OR · risk variant | 2.76 OR · risk variant | expected reference genotype | Higher exposure at standard dose |
| MTHFR | 1.53 OR · risk variant | 2.09 OR · risk variant | expected reference genotype | Reduced folate turnover |