DeepGene damage signature
SyntheticSynthetic demo data2 samples: baseline day 0 · retest day 90
Damage score · retest day 90
36/100
vs baseline (day 0)
-16
6 improved · 2 worsened
synthetic signature · consistent with this patient's biology
- 3 opportunists above range: Escherichia coli, Klebsiella pneumoniae, Streptococcus gallolyticus
- 2 keystone species absent
- 4 resistance genes
Pathogens / opportunists3/5
Keystone species2/8
↓ from 3
Diversity0/2
↓ from 1
Metabolic modules1/4
↑ from 0
Vitamin synthesis2/7
Oral translocation1/1
Host DNA0/1
Tissue recycling0/1
↓ from 1
Central mechanisms0/2
Virulence factors2/2
↓ from 3
Antibiotic resistance genes4/4
↓ from 5
Genetic predisposition1/1
Opportunists above range
Escherichia coli 11.003% AR
Klebsiella pneumoniae 3.301% AR
Streptococcus gallolyticus 1.1% AR
Keystone species absent
Akkermansia muciniphila, Bifidobacterium longum
Capacity
Shannon 3.2 · butyrate 719 CPM · SCFA 1202
H2S above band
2 vitamins below
Host & mechanisms
tissue recycling 29/100
oral translocation 2.53% AR
4 resistance genes · 2 virulence factors
Import a sample
A baseline sample re-initializes this patient's microbiome, pathways and predispositions from the measurement; a retest adds a comparison and updates them. Every theory, steering gain and dietary sensitivity downstream is then conditioned on the measured signature.
All elements · baseline → latest
Value, status vs the expected range, and the implication on health. Changes coloured: green improved / resolved, red worsened / new.
Pathogens / opportunists · 5
| Escherichia coli | 14.871 % AR · above range | 11.003 % AR · above range | expected <= 1% | In excess raises LPS load and zonulin release, opening tight junctions. |
| Klebsiella pneumoniae | 4.461 % AR · above range | 3.301 % AR · above range | expected <= 0.3% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Enterococcus faecium | 7.436 % AR · above range | 0.097 % AR · in range(improved) | expected <= 0.5% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Streptococcus gallolyticus | 0.065 % AR · in range | 1.1 % AR · above range(worsened) | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Clostridioides difficile | 0.036 % AR · in range | 0.059 % AR · in range | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
Keystone species · 8
| Akkermansia muciniphila | 0 % AR · absent | 0 % AR · absent | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Bifidobacterium longum | 0 % AR · absent | 0 % AR · absent | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Butyricicoccus pullicaecorum | 0 % AR · absent | 1.16 % AR · in range(improved) | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Eubacterium rectale | 0.88 % AR · in range | 0.96 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Faecalibacterium prausnitzii | 0.98 % AR · in range | 0.93 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Lactobacillus species | 0.83 % AR · in range | 0.97 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Roseburia intestinalis | 1.31 % AR · in range | 0.25 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Ruminococcus bromii | 0.72 % AR · in range | 0.75 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
Diversity · 2
| indice Shannon | 2.83 · below range | 3.2 · in range(improved) | expected >= 3.0 | Low diversity: fewer reserve metabolic routes, slower recovery after perturbation. |
| numar de specii detectate | 127 specii · in range | 131 specii · in range | expected >= 100 | Species count below reference. |
Metabolic modules · 4
| Butyrate production | 670 CPM · in range | 719 CPM · in range | expected 255.83-1089.91 CPM | Butyrate is the main colonocyte fuel and barrier signal. |
| Short Chain Fatty Acid Production | 1049 CPM · in range | 1202 CPM · in range | expected 535.03-1572.59 CPM | Total SCFA capacity. |
| GABA production | 368 CPM · in range | 420 CPM · in range | expected 87.31-766.53 CPM | Gut–brain axis capacity. |
| H2S production (sulfate reduction) | 117 CPM · in range | 434 CPM · above range(worsened) | expected banda de referinta | Hydrogen sulfide above band irritates the mucosa. |
Vitamin synthesis · 7
| Vitamin B1 - Thiamin | 450 CPM · below range | 536 CPM · below range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B2 - Riboflavin | 416 CPM · below range | 150 CPM · below range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B5 - Pantothenic acid | 3436 CPM · in range | 2950 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B6 - Pyridoxine | 2683 CPM · in range | 3180 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B7 - Biotin | 3700 CPM · in range | 4200 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B9 - Folate | 3665 CPM · in range | 3766 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B12 - Cobalamin | 4392 CPM · in range | 3378 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
Oral translocation · 1
| Translocare orala (indice) | 3.4 % AR · above range | 2.53 % AR · above range | expected <= 2% | Oral taxa in stool: reduced gastric barrier or dysbiosis. |
Host DNA · 1
| fragmentare mixta | 163 pb · in range | 165 pb · in range | expected 150-170 pb | Host cell-free DNA fragmentation pattern. |
Tissue recycling · 1
| indice de reciclare tisulara | 42 /100 · above range | 29 /100 · in range(improved) | expected < 35 | Epithelial turnover. |
Central mechanisms · 2
| molecular_mimicry | 60 /100 · in range | 54 /100 · in range | expected < 65 | Cross-reactive antigen load. |
| estrobolome | 55 /100 · in range | 54 /100 · in range | expected < 65 | Estrogen-recycling capacity. |
Virulence factors · 3
| fimD outer membrane usher | 50 potriviri/M · present | 99 potriviri/M · present | expected absent | Virulence factor detected. |
| chuA heme/hemoglobin receptor | 63 potriviri/M · present | 26 potriviri/M · present | expected absent | Virulence factor detected. |
| irp2 yersiniabactin synthetase | 51 potriviri/M · present | resolved(resolved) | expected absent | Virulence factor detected. |
Antibiotic resistance genes · 5
| sul1 | 7.9 citiri/M · present | 5.2 citiri/M · present | expected nedetectat | Resistance gene detected. |
| sul2 | 6.9 citiri/M · present | 5.1 citiri/M · present | expected nedetectat | Resistance gene detected. |
| tet(O/M/O) | 7.1 citiri/M · present | 5.6 citiri/M · present | expected nedetectat | Resistance gene detected. |
| Ecol_ampC_BLA | 7.4 citiri/M · present | 3.1 citiri/M · present | expected nedetectat | Resistance gene detected. |
| aadA | 10.4 citiri/M · present | resolved(resolved) | expected nedetectat | Resistance gene detected. |
Genetic predisposition · 1
| CYP2D6 | 1.54 OR · risk variant | 2.21 OR · risk variant | expected reference genotype | Expected exposure |