DeepGene damage signature
SyntheticSynthetic demo data2 samples: baseline day 0 · retest day 90
Damage score · retest day 90
63/100
vs baseline (day 0)
-1
3 improved · 4 worsened
synthetic signature · consistent with this patient's biology
- 2 opportunists above range: Enterococcus faecium, Clostridioides difficile
- 4 keystone species absent
- Shannon 2.63 (expected ≥ 3)
- 8 resistance genes
- Tissue recycling index 46
Pathogens / opportunists2/5
↓ from 3
Keystone species4/8
↑ from 3
Diversity2/2
↑ from 1
Metabolic modules1/4
Vitamin synthesis3/7
Oral translocation1/1
Host DNA0/1
↓ from 1
Tissue recycling1/1
Central mechanisms0/2
Virulence factors4/4
↑ from 3
Antibiotic resistance genes8/8
Genetic predisposition1/1
Opportunists above range
Enterococcus faecium 9.962% AR
Clostridioides difficile 1.992% AR
Keystone species absent
Akkermansia muciniphila, Bifidobacterium longum, Butyricicoccus pullicaecorum, Eubacterium rectale
Capacity
Shannon 2.63 · butyrate 578 CPM · SCFA 940
H2S above band
3 vitamins below
Host & mechanisms
tissue recycling 46/100
oral translocation 4.53% AR
8 resistance genes · 4 virulence factors
Import a sample
A baseline sample re-initializes this patient's microbiome, pathways and predispositions from the measurement; a retest adds a comparison and updates them. Every theory, steering gain and dietary sensitivity downstream is then conditioned on the measured signature.
All elements · baseline → latest
Value, status vs the expected range, and the implication on health. Changes coloured: green improved / resolved, red worsened / new.
Pathogens / opportunists · 5
| Escherichia coli | 0.197 % AR · in range | 0.17 % AR · in range | expected <= 1% | In excess raises LPS load and zonulin release, opening tight junctions. |
| Klebsiella pneumoniae | 5.784 % AR · above range | 0.167 % AR · in range(improved) | expected <= 0.3% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Enterococcus faecium | 9.64 % AR · above range | 9.962 % AR · above range | expected <= 0.5% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Streptococcus gallolyticus | 1.928 % AR · above range | 0.041 % AR · in range(improved) | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Clostridioides difficile | 0.018 % AR · in range | 1.992 % AR · above range(worsened) | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
Keystone species · 8
| Akkermansia muciniphila | 0 % AR · absent | 0 % AR · absent | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Bifidobacterium longum | 0 % AR · absent | 0 % AR · absent | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Butyricicoccus pullicaecorum | 0 % AR · absent | 0 % AR · absent | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Eubacterium rectale | 0.41 % AR · in range | 0 % AR · absent(worsened) | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Faecalibacterium prausnitzii | 0.96 % AR · in range | 0.93 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Lactobacillus species | 1.34 % AR · in range | 1.44 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Roseburia intestinalis | 1.16 % AR · in range | 0.82 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Ruminococcus bromii | 0.29 % AR · in range | 1.32 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
Diversity · 2
| indice Shannon | 2.53 · below range | 2.63 · below range | expected >= 3.0 | Low diversity: fewer reserve metabolic routes, slower recovery after perturbation. |
| numar de specii detectate | 108 specii · in range | 95 specii · below range(worsened) | expected >= 100 | Species count below reference. |
Metabolic modules · 4
| Butyrate production | 596 CPM · in range | 578 CPM · in range | expected 255.83-1089.91 CPM | Butyrate is the main colonocyte fuel and barrier signal. |
| Short Chain Fatty Acid Production | 956 CPM · in range | 940 CPM · in range | expected 535.03-1572.59 CPM | Total SCFA capacity. |
| GABA production | 324 CPM · in range | 319 CPM · in range | expected 87.31-766.53 CPM | Gut–brain axis capacity. |
| H2S production (sulfate reduction) | 429 CPM · above range | 317 CPM · above range | expected banda de referinta | Hydrogen sulfide above band irritates the mucosa. |
Vitamin synthesis · 7
| Vitamin B1 - Thiamin | 393 CPM · below range | 362 CPM · below range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B2 - Riboflavin | 339 CPM · below range | 459 CPM · below range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B5 - Pantothenic acid | 472 CPM · below range | 286 CPM · below range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B6 - Pyridoxine | 2923 CPM · in range | 3190 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B7 - Biotin | 3468 CPM · in range | 2949 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B9 - Folate | 2736 CPM · in range | 3270 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B12 - Cobalamin | 4332 CPM · in range | 3706 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
Oral translocation · 1
| Translocare orala (indice) | 4.39 % AR · above range | 4.53 % AR · above range | expected <= 2% | Oral taxa in stool: reduced gastric barrier or dysbiosis. |
Host DNA · 1
| fragmentare mixta | 242 pb · atypical | 166 pb · in range(improved) | expected 150-170 pb | Host cell-free DNA fragmentation pattern. |
Tissue recycling · 1
| indice de reciclare tisulara | 46 /100 · above range | 46 /100 · above range | expected < 35 | Epithelial turnover. |
Central mechanisms · 2
| molecular_mimicry | 65 /100 · in range | 62 /100 · in range | expected < 65 | Cross-reactive antigen load. |
| estrobolome | 60 /100 · in range | 64 /100 · in range | expected < 65 | Estrogen-recycling capacity. |
Virulence factors · 4
| fimD outer membrane usher | 77 potriviri/M · present | 54 potriviri/M · present | expected absent | Virulence factor detected. |
| chuA heme/hemoglobin receptor | 96 potriviri/M · present | 52 potriviri/M · present | expected absent | Virulence factor detected. |
| irp2 yersiniabactin synthetase | 99 potriviri/M · present | 37 potriviri/M · present | expected absent | Virulence factor detected. |
| espX4 type III secretion | — | 22 potriviri/M · present(new) | expected absent | Virulence factor detected. |
Antibiotic resistance genes · 8
| sul1 | 3.7 citiri/M · present | 10.5 citiri/M · present | expected nedetectat | Resistance gene detected. |
| sul2 | 6.3 citiri/M · present | 4.6 citiri/M · present | expected nedetectat | Resistance gene detected. |
| tet(O/M/O) | 4 citiri/M · present | 2 citiri/M · present | expected nedetectat | Resistance gene detected. |
| Ecol_ampC_BLA | 4.9 citiri/M · present | 3.1 citiri/M · present | expected nedetectat | Resistance gene detected. |
| aadA | 4.4 citiri/M · present | 7 citiri/M · present | expected nedetectat | Resistance gene detected. |
| dfrA1 | 4.2 citiri/M · present | 10.3 citiri/M · present | expected nedetectat | Resistance gene detected. |
| APH(6)-Id | 7.8 citiri/M · present | 3.1 citiri/M · present | expected nedetectat | Resistance gene detected. |
| Erm(49) | 1.1 citiri/M · present | 10.8 citiri/M · present | expected nedetectat | Resistance gene detected. |
Genetic predisposition · 1
| CYP2D6 | 3.29 OR · risk variant | 3.27 OR · risk variant | expected reference genotype | Expected exposure |