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Patient P-03442

Synthetic patientONX-7 · Day 140 · 25–34 · M · baseline S11Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Favorable
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
13%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 ONX-7 started — Baseline state S11
  2. Day 15 Trajectory diverged from prediction — Observed response fell below the model's expected path.
  3. Day 18 DT-01 recommended — Dosing / Timing Recommendation DT-01
  4. Day 19 Patient accepted — Started DT-01 in the companion
  5. Day 24 GI symptom burden −26% vs expected — Dosing / Timing Recommendation DT-01
  6. Day 30 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 15.

Primary contributors, last 14 days
  • Nutritional resilience+9
  • GI instability-7
  • Inflammatory activity-7
  • Treatment adherence-6

What helped?

  • Dosing / Timing Recommendation DT-01Day 18
    Result: symptom burden −26%
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Energy level
Daily log
5.6/10
stable · -0.0 vs previous 14 d
Stress level
Daily log
4.1/10
worsening · +0.2 vs previous 14 d
Pessimism score
Daily log
4.4/10
stable · -0.0 vs previous 14 d
Sleep quality
Wearable
40.5/100
stable · +1.2 vs previous 14 d
Libido
Daily log
4.3/10
stable · -0.2 vs previous 14 d
HRV
Wearable
60.9 ms
stable · -0.0 vs previous 14 d
Toxicity
Blood
16.4/100
improving · -0.8 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →

Heading towards restoration · 70 from the failing basin, 27 from restoration.

Would help
  • No untried action with strong evidence. Compose one from primitives.
  • More protein
    GI -5.6 next day on high-intake days · n 24
Would not help
  • AD-05 Adherence Support
    only 29% improved among 14 similar
  • Keep histamine low
    GI +5.3 next day on high-intake days · n 17
  • Keep lactose low
    GI +4.9 next day on high-intake days · n 21
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Protein
    -5.6supporter · 95%
  • Histamine load
    +5.3detractor · 95%
  • Lactose
    +4.9detractor · 95%
  • Dietary fat load
    +2.6no signal · 51%
  • Caffeine
    -2no signal · 40%
  • Alcohol
    -0.6no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Mucosal barrier integrity ↓70
    • DNAFUT2 non-secretor lowers mucosal fucosylation
    • MicrobiomeAkkermansia low → thinner mucus layer
    • WearableSleep 5.9 h, below personal baseline
  • Butyrate / short-chain fatty acid production ↓25
    • MicrobiomeF. prausnitzii depleted
  • Inflammatory signalling ↓20
    • MicrobiomeBacteroides fragilis expansion
  • Autonomic recovery ↓20
    • WearableShort sleep window
DNA
Fictional pharmacogenomic panel
  • FUT2 rs601338 AA (non-secretor)
    Reduced mucosal fucosylation
  • CYP2D6 Normal metabolizer
    Expected exposure
  • MTHFR C677T
    Reduced folate turnover
Microbiome
Shannon diversity 3.1 · butyrate capacity 45/100
  • Akkermansia muciniphilaLow
  • Faecalibacterium prausnitziiLow
  • Bacteroides fragilisHigh
  • Bifidobacterium longumLow
  • EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
HRV
67 ms
Sleep
6.2 h
Steps
7,301
Resting HR
61 bpm
Daily log: GI score 21, nutritional resilience 66, adherence 94.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Keep meals regular; three to four moderate portions spaced through the day
  • Include a cooked vegetable portion with each main meal
  • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
  • Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
  • Log the daily check-in; one line is enough
  • Keep the current walking rhythm
  • Protect a 7.5-hour sleep window; screens off 30 minutes before
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the scheduled dose as agreed with your care team
  • No additional supplements this week
  • Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
PatientSimilarityBaselineInterventionOutcomeResponse today
P-0340857%S09HY-01improved53
P-0324454%S08DT-01improved53
P-0311453%S11DT-01improved48
P-0314351%S11DT-01improved49
P-0326851%S15DT-01improved56
P-0319350%S13DT-01improved53
P-0321549%S16HY-01improved44
P-0339247%S15GI-04improved52
P-0321346%S02DT-01improved59
P-0317944%S05GI-04improved52
P-0314442%S16HY-01improved52
P-0323342%S19DT-01improved47