Patient P-02008
Therapy response
Unstable
Tolerance
Deteriorating
GI state
Improving
Inflammatory state
Favorable
Nutritional resilience
Favorable
Discontinuation risk
19%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S20
- Day 38 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 38.
Primary contributors, last 14 days
- Toxicity+7
- GI instability-5
- Treatment adherence-5
- Nutritional resilience+3
- Inflammatory activity+2
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable39 min
stable · +0.8 vs previous 14 d
Sleep duration
Wearable6 h
stable · -0.2 vs previous 14 d
Energy level
Daily log4.9/10
stable · -0.1 vs previous 14 d
Steps
Wearable5,277
stable · -34 vs previous 14 d
GI burden
Companion16.8/100
worsening · +1.9 vs previous 14 d
Adherence
Companion81.5 %
stable · -1.5 vs previous 14 d
Sleep quality
Wearable25.3/100
worsening · -4.5 vs previous 14 d
Glucose, CGM daily mean
CGM136 mg/dL
stable · +2.5 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 66 from the failing basin, 47 from restoration.
Would help
- No untried action with strong evidence. Compose one from primitives.
- More proteinGI -2.1 next day on high-intake days · n 18
Would not help
- BR-03 Behavioural Recommendationonly 22% improved among 9 similar
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-2.1supporter · 80%
- Simple carbohydrates+1.3no signal · 46%
- Ultra-processed food-1.3no signal · 44%
- Histamine load+1no signal · 32%
- Caffeine+0.9no signal · 28%
- Alcohol+0.4no signal · 15%
- Dietary fat load-0.1no signal · 15%
- Insoluble fibre+0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓40
- MicrobiomeAkkermansia low → thinner mucus layer
- WearableSleep 6.0 h, below personal baseline
- Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
- Autonomic recovery ↓20
- WearableShort sleep window
- Inflammatory signalling ↑15
- WearableHRV 36 ms, trending down
DNA
Fictional pharmacogenomic panel
- CYP2D6 Normal metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 3.6 · butyrate capacity 57/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 32 ms
- Sleep
- 6.0 h
- Steps
- 4,991
- Resting HR
- 68 bpm
Daily log: GI score 17, nutritional resilience 63, adherence 82.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02552 | 48% | S07 | AD-05 | no change | 29 |
| P-02093 | 35% | S05 | AD-05 | no change | 40 |
| P-02285 | 33% | S14 | AD-05 | no change | 39 |
| P-02031 | 30% | S12 | AD-05 | improved | 47 |
| P-02564 | 46% | S15 | BR-03 | improved | 32 |
| P-02522 | 36% | S01 | BR-03 | no change | 40 |
| P-02325 | 34% | S19 | BR-03 | no change | 33 |
| P-02308 | 32% | S13 | BR-03 | no change | 27 |
| P-02087 | 31% | S01 | BR-03 | no change | 40 |
| P-02331 | 31% | S14 | BR-03 | improved | 34 |
| P-02439 | 31% | S08 | BR-03 | no change | 40 |
| P-02267 | 28% | S09 | BR-03 | no change | 45 |