Patient P-02160
Synthetic patientMETA-24 · Day 146 · 25–34 · F · baseline S03Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Stable
GI state
Improving
Inflammatory state
Stable
Nutritional resilience
Improving
Discontinuation risk
43%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S03
- Day 70 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 70.
Primary contributors, last 14 days
- Treatment adherence-12
- GI instability-6
- Nutritional resilience+4
- Toxicity-2
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
55%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 85% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable66 min
worsening · -3.5 vs previous 14 d
Sleep duration
Wearable6.3 h
worsening · -0.3 vs previous 14 d
Energy level
Daily log3.9/10
worsening · -0.9 vs previous 14 d
Steps
Wearable6,352
worsening · -658 vs previous 14 d
GI burden
Companion43.9/100
worsening · +9.2 vs previous 14 d
Adherence
Companion74.4 %
worsening · -6.3 vs previous 14 d
Sleep quality
Wearable25.3/100
worsening · -3.7 vs previous 14 d
Glucose, CGM daily mean
CGM136 mg/dL
stable · +5.4 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 37 from the failing basin, 50 from restoration.
Would help
- GI-04 GI Support Protocol76% improved among 67 similar · onset 8 d · confidence 51%
- ME-01 Monitoring Escalation100% improved among 33 similar · onset 3 d · confidence 55%
- SC-12 Supportive Compound76% improved among 25 similar · onset 6 d · confidence 55%
- More proteinGI -5.9 next day on high-intake days · n 20
Would not help
- Keep fat lowGI +5 next day on high-intake days · n 21
- Keep ultra-processed lowGI +5 next day on high-intake days · n 20
- Keep simple carbs lowGI +4 next day on high-intake days · n 19
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-5.9supporter · 95%
- Dietary fat load+5detractor · 95%
- Ultra-processed food+5detractor · 95%
- Simple carbohydrates+4detractor · 95%
- Histamine load+3.4detractor · 92%
- Caffeine-1no signal · 18%
- Insoluble fibre-0.9no signal · 19%
- Alcohol-0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 23/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↓65
- DNAIL6 -174 variant raises baseline inflammatory tone
- BloodInflammatory load index 50
- WearableHRV 23 ms, trending down
- Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Autonomic recovery ↑45
- WearableResting HR 77 bpm
- WearableShort sleep window
- Drug metabolism and exposure ↑20
- BloodToxicity index 45
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Rapid metabolizerExpected exposure
Microbiome
Shannon diversity 1.9 · butyrate capacity 23/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 22 ms
- Sleep
- 5.7 h
- Steps
- 6,662
- Resting HR
- 78 bpm
Daily log: GI score 44, nutritional resilience 49, adherence 74.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02115 | 27% | S14 | GI-04 | improved | 75 |
| P-02575 | 26% | S14 | ME-01 | improved | 73 |
| P-02553 | 26% | S13 | — | — | 71 |
| P-02550 | 28% | S01 | — | — | 70 |
| P-02192 | 27% | S05 | — | — | 69 |
| P-02659 | 31% | S09 | — | — | 69 |
| P-02293 | 25% | S15 | HY-01 | no change | 68 |
| P-02591 | 31% | S13 | — | — | 68 |
| P-02090 | 27% | S04 | — | — | 68 |
| P-02265 | 33% | S07 | GI-04 | no change | 67 |
| P-02530 | 35% | S07 | — | — | 67 |
| P-02194 | 26% | S03 | — | — | 67 |