700 patients110,866 observations180 daysLIVE

Patient P-02182

Synthetic patientMETA-24 · Day 177 · 55–64 · M · baseline S12Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
9%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 startedBaseline state S12
  2. Day 24 Trajectory diverged from predictionObserved response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 24.

Primary contributors, last 14 days
  • Inflammatory activity-12
  • Nutritional resilience+10
  • GI instability-9
  • Toxicity-7
  • Treatment adherence-5

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Active minutes
    Wearable
    77 min
    worsening · -7.2 vs previous 14 d
    Sleep duration
    Wearable
    7.8 h
    stable · -0.1 vs previous 14 d
    Energy level
    Daily log
    7/10
    stable · +0.0 vs previous 14 d
    Steps
    Wearable
    8,478
    stable · -249 vs previous 14 d
    GI burden
    Companion
    12.9/100
    worsening · +1.1 vs previous 14 d
    Adherence
    Companion
    82.2 %
    stable · -1.4 vs previous 14 d
    Sleep quality
    Wearable
    65.4/100
    stable · -1.4 vs previous 14 d
    Glucose, CGM daily mean
    CGM
    126 mg/dL
    stable · -1.0 vs previous 14 d
    This trajectory is doing well — what to keep, what to watch
    Steering view →

    Heading towards restoration · 78 from the failing basin, 44 from restoration.

    Good elements to keep
    • Protein (supports)
      perturbation · steering +8.9
    • Butyrate producers intact
      hidden · steering +7.5
    • Dietary fat load (supports)
      perturbation · steering +4.1
    • Protein
      supporter · GI -4.8 next day
    • Dietary fat load
      supporter · GI -3.2 next day
    Main detractors to watch
    • Poor metabolizer
      hidden · steering -12.7
    • Low microbial diversity
      hidden · steering -7.7
    • Bacteroides fragilis elevated
      hidden · steering -7.4
    • Simple carbohydrates
      perturbation · steering -6.3
    • Ultra-processed food
      detractor · GI +3.8 next day
    • Simple carbohydrates
      detractor · GI +3.3 next day
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Protein
      -4.8supporter · 95%
    • Ultra-processed food
      +3.8detractor · 95%
    • Simple carbohydrates
      +3.3detractor · 91%
    • Dietary fat load
      -3.2supporter · 63%
    • Caffeine
      +2.4no signal · 51%
    • Insoluble fibre
      +0.9no signal · 20%
    • Alcohol
      +0.6no signal · 15%
    • Histamine load
      +0.2no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Drug metabolism and exposure 40
      • DNACYP2D6 poor metabolizer → higher exposure
    • Inflammatory signalling 20
      • MicrobiomeBacteroides fragilis expansion
    DNA
    Fictional pharmacogenomic panel
    • CYP2D6 Poor metabolizer
      Higher exposure at standard dose
    • GLP1R rs6923761 A
      Altered receptor sensitivity
    • MTHFR C677T
      Reduced folate turnover
    Microbiome
    Shannon diversity 2.9 · butyrate capacity 75/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisHigh
    • Bifidobacterium longumNormal
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    59 ms
    Sleep
    7.7 h
    Steps
    8,564
    Resting HR
    72 bpm
    Daily log: GI score 13, nutritional resilience 74, adherence 82.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Eat slowly and stop at comfortable fullness — smaller volume, more often
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the dose at the same time relative to your evening meal
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0233149%S14BR-03improved34
    P-0201646%S20DT-01improved27
    P-0256435%S15BR-03improved32
    P-0203134%S12AD-05improved47
    P-0239133%S19HY-01improved53
    P-0247932%S13DT-01improved48
    P-0249432%S09GI-04improved47
    P-0260232%S20HY-01improved52
    P-0248431%S15GI-04improved49
    P-0203330%S06GI-04improved51
    P-0230330%S15GI-04improved48
    P-0233930%S03DT-01improved50