Patient P-02182

Synthetic patientMETA-24 · Day 177 · 55–64 · M · baseline S12Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Improving

GI state

Improving

Inflammatory state

Improving

Nutritional resilience

Improving

Discontinuation risk

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S12
Day 24 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 24.

Primary contributors, last 14 days

Inflammatory activity-12
Nutritional resilience+10
GI instability-9
Toxicity-7
Treatment adherence-5

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

77 min

worsening · -7.2 vs previous 14 d

Sleep duration

Wearable

7.8 h

stable · -0.1 vs previous 14 d

Energy level

Daily log

7/10

stable · +0.0 vs previous 14 d

Steps

Wearable

8,478

stable · -249 vs previous 14 d

GI burden

Companion

12.9/100

worsening · +1.1 vs previous 14 d

Adherence

Companion

82.2 %

stable · -1.4 vs previous 14 d

Sleep quality

Wearable

65.4/100

stable · -1.4 vs previous 14 d

Glucose, CGM daily mean

CGM

126 mg/dL

stable · -1.0 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 78 from the failing basin, 44 from restoration.

Good elements to keep

Protein (supports)
perturbation · steering +8.9
Butyrate producers intact
hidden · steering +7.5
Dietary fat load (supports)
perturbation · steering +4.1
Protein
supporter · GI -4.8 next day
Dietary fat load
supporter · GI -3.2 next day

Main detractors to watch

Poor metabolizer
hidden · steering -12.7
Low microbial diversity
hidden · steering -7.7
Bacteroides fragilis elevated
hidden · steering -7.4
Simple carbohydrates
perturbation · steering -6.3
Ultra-processed food
detractor · GI +3.8 next day
Simple carbohydrates
detractor · GI +3.3 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Protein
-4.8supporter · 95%
Ultra-processed food
+3.8detractor · 95%
Simple carbohydrates
+3.3detractor · 91%
Dietary fat load
-3.2supporter · 63%
Caffeine
+2.4no signal · 51%
Insoluble fibre
+0.9no signal · 20%
Alcohol
+0.6no signal · 15%
Histamine load
+0.2no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure
Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion

DNA

Fictional pharmacogenomic panel

CYP2D6 Poor metabolizer
Higher exposure at standard dose
GLP1R rs6923761 A
Altered receptor sensitivity
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 2.9 · butyrate capacity 75/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumNormal
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 59 ms
Sleep: 7.7 h
Steps: 8,564
Resting HR: 72 bpm

Daily log: GI score 13, nutritional resilience 74, adherence 82.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02552	37%	S07	AD-05	no change	29
P-02093	35%	S05	AD-05	no change	40
P-02031	34%	S12	AD-05	improved	47
P-02285	34%	S14	AD-05	no change	39
P-02331	49%	S14	BR-03	improved	34
P-02522	40%	S01	BR-03	no change	40
P-02439	37%	S08	BR-03	no change	40
P-02325	36%	S19	BR-03	no change	33
P-02564	35%	S15	BR-03	improved	32
P-02087	31%	S01	BR-03	no change	40
P-02308	30%	S13	BR-03	no change	27
P-02267	28%	S09	BR-03	no change	45