Patient P-02200

Synthetic patientMETA-24 · Day 175 · 35–44 · F · baseline S13Steering view · 3D Open companion preview

Therapy response

Stable

Tolerance

Favorable

GI state

Favorable

Inflammatory state

Favorable

Nutritional resilience

Favorable

Discontinuation risk

14%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S13
Day 16 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 22 HY-01 recommended — Hydration Protocol HY-01
Day 23 Patient declined — Not now

What changed?

Trajectory began diverging from predicted response on Day 16.

Primary contributors, last 14 days

Treatment adherence-4
Toxicity+4

What helped?

Hydration Protocol HY-01Day 22
Declined by patient

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

47 min

stable · +1.9 vs previous 14 d

Sleep duration

Wearable

7.8 h

stable · +0.1 vs previous 14 d

Energy level

Daily log

6.5/10

stable · -0.2 vs previous 14 d

Steps

Wearable

6,084

improving · +404 vs previous 14 d

GI burden

Companion

21.1/100

improving · -4.2 vs previous 14 d

Adherence

Companion

93.8 %

stable · +3.1 vs previous 14 d

Sleep quality

Wearable

58/100

stable · +1.3 vs previous 14 d

Glucose, CGM daily mean

CGM

135 mg/dL

stable · -0.4 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading drifting · 67 from the failing basin, 32 from restoration.

Good elements to keep

Protein (supports)
perturbation · steering +6.4
Protein
supporter · GI -3.7 next day

Main detractors to watch

Low butyrate capacity
hidden · steering -17.5
FUT2 non-secretor
hidden · steering -10.6
Low microbial diversity
hidden · steering -7.7
Bacteroides fragilis elevated
hidden · steering -7.4
Ultra-processed food
detractor · GI +3.4 next day
Histamine load
detractor · GI +2.5 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Protein
-3.7supporter · 95%
Ultra-processed food
+3.4detractor · 95%
Histamine load
+2.5detractor · 82%
Simple carbohydrates
+2detractor · 57%
Dietary fat load
+1.9detractor · 65%
Insoluble fibre
-1.4no signal · 38%
Caffeine
-0.4no signal · 15%
Alcohol
+0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
Butyrate / short-chain fatty acid production ↓35
- MicrobiomeButyrate capacity 30/100
Inflammatory signalling ↑20
- MicrobiomeBacteroides fragilis expansion

DNA

Fictional pharmacogenomic panel

FUT2 rs601338 AA (non-secretor)
Reduced mucosal fucosylation
CYP2D6 Intermediate metabolizer
Expected exposure
GLP1R rs6923761 A
Altered receptor sensitivity

Microbiome

Shannon diversity 2.2 · butyrate capacity 30/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 37 ms
Sleep: 7.3 h
Steps: 6,256
Resting HR: 62 bpm

Daily log: GI score 21, nutritional resilience 66, adherence 94.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02093	42%	S05	AD-05	no change	40
P-02285	39%	S14	AD-05	no change	39
P-02031	37%	S12	AD-05	improved	47
P-02087	41%	S01	BR-03	no change	40
P-02267	39%	S09	BR-03	no change	45
P-02522	37%	S01	BR-03	no change	40
P-02439	36%	S08	BR-03	no change	40
P-02280	34%	S07	BR-03	no change	50
P-02308	34%	S13	BR-03	no change	27
P-02483	34%	S06	BR-03	no change	64
P-02564	33%	S15	BR-03	improved	32
P-02638	33%	S01	BR-03	improved	41