Patient P-02252
Synthetic patientMETA-24 · Day 135 · 65–74 · F · baseline S02Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Deteriorating
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Unstable
Discontinuation risk
69%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S02
- Day 29 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 29.
Primary contributors, last 14 days
- GI instability+18
- Inflammatory activity+18
- Toxicity+16
- Treatment adherence-12
- Nutritional resilience-11
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
58%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 87% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable9 min
worsening · -6.0 vs previous 14 d
Sleep duration
Wearable5.9 h
worsening · -0.3 vs previous 14 d
Energy level
Daily log2.5/10
worsening · -0.9 vs previous 14 d
Steps
Wearable505
worsening · -843 vs previous 14 d
GI burden
Companion57/100
worsening · +11.4 vs previous 14 d
Adherence
Companion79.8 %
worsening · -5.3 vs previous 14 d
Sleep quality
Wearable32.3/100
worsening · -8.1 vs previous 14 d
Glucose, CGM daily mean
CGM150 mg/dL
worsening · +6.9 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 44 from the failing basin, 54 from restoration.
Would help
- GI-04 GI Support Protocol85% improved among 48 similar · onset 8 d · confidence 53%
- ME-01 Monitoring Escalation100% improved among 21 similar · onset 3 d · confidence 64%
- NP-02 Dietary Support Protocol73% improved among 15 similar · onset 10 d · confidence 64%
- More proteinGI -3.3 next day on high-intake days · n 13
Would not help
- Keep ultra-processed lowGI +3 next day on high-intake days · n 25
- Keep fat lowGI +2.3 next day on high-intake days · n 24
- Keep alcohol lowGI +1.9 next day on high-intake days · n 20
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-3.3supporter · 95%
- Ultra-processed food+3detractor · 95%
- Dietary fat load+2.3detractor · 95%
- Alcohol+1.9detractor · 81%
- Simple carbohydrates+1.8detractor · 69%
- Insoluble fibre+0.9no signal · 29%
- Histamine load-0.5no signal · 18%
- Caffeine+0.4no signal · 16%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓60
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 57 and rising
- WearableSleep 5.9 h, below personal baseline
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 40/100
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↑50
- DNAIL6 -174 variant raises baseline inflammatory tone
- BloodInflammatory load index 57
- Autonomic recovery ↓40
- Wearable505 steps/day
- WearableShort sleep window
- Drug metabolism and exposure ↑20
- BloodToxicity index 43
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Intermediate metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 2.6 · butyrate capacity 40/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 46 ms
- Sleep
- 6.6 h
- Steps
- 1,663
- Resting HR
- 65 bpm
Daily log: GI score 57, nutritional resilience 42, adherence 80.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02309 | 50% | S09 | — | — | 67 |
| P-02659 | 50% | S09 | — | — | 69 |
| P-02078 | 42% | S04 | — | — | 56 |
| P-02229 | 38% | S20 | — | — | 56 |
| P-02233 | 38% | S16 | CR-01 | improved | 66 |
| P-02009 | 36% | S08 | CR-01 | improved | 64 |
| P-02115 | 36% | S14 | GI-04 | improved | 75 |
| P-02321 | 36% | S17 | GI-04 | improved | 54 |
| P-02595 | 35% | S02 | — | — | 53 |
| P-02060 | 33% | S14 | GI-04 | improved | 54 |
| P-02134 | 33% | S11 | — | — | 62 |
| P-02160 | 33% | S03 | — | — | 45 |