Patient P-02299
Metabolic response 84 at the day-84 endpoint (observed).
Responding: response probability 92%, metabolic response 99 today; biology is not blocking the drug.
No side effect starting: nausea / gi symptoms 13, tolerability burden 9, no drift from the model.
40 of 61 scheduled doses in the last 60 days are biologically confirmed (66%); 19 were logged but show no dose signature. Dose signature: resting HR +3 bpm, HRV −9 ms.
Trajectory is stable relative to similar patients; keep the current content.
- 🍽Keep meals regular; three to four moderate portions spaced through the day
- 🍽Include a cooked vegetable portion with each main meal
- ✓Log the daily check-in; one line is enough
- ✓Keep the current walking rhythm
- 💊Take the dose at the same time relative to your evening meal
- 💊No additional supplements this week
Adherence is not the problem.
sleep quality falling under 35 while GI rises
P-02299 is on day 143 of META-24 (SR, baseline S11): response improving, tolerance favorable, GI improving. Over 14 days response moved +15 and GI -13; discontinuation risk is 9%. The state is between basins, heading towards restoration.
Butyrate capacity 53/100, diversity 4.6, normal metabolizer. Pushing it down: Escherichia coli 11.584% (LPS load) (-33.5), Tissue recycling 36/100 (-16.1), Antibiotic course (-4.7). Pulling it up: Protein (supports) (+26.2), Butyrate producers intact (+14.3). From the daily log: protein -6 GI next day.
No action has been tried yet.
No action is indicated now; the trajectory is stable relative to similar patients.
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and events- Day 0 META-24 started — Baseline state S11
What changed?
Trajectory is tracking the baseline prediction.
- GI instability-13
- Inflammatory activity-10
- Nutritional resilience+6
- Treatment adherence-5
What helped?
No interventions yet.
Daily trackers
Asset settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Heading towards restoration · 105 from the failing basin, 22 from restoration.
- Protein (supports)perturbation · steering +26.2
- Butyrate producers intacthidden · steering +14.3
- Daily walks resumedperturbation · steering +3.3
- Proteinsupporter · GI -6 next day
- Escherichia coli 11.584% (LPS load)hidden · steering -33.5
- Tissue recycling 36/100hidden · steering -16.1
- Antibiotic courseperturbation · steering -4.7
- Low-HRV stretchperturbation · steering -2.7
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-6supporter · 95%
- Ultra-processed food+2.5no signal · 53%
- Insoluble fibre-1.4no signal · 32%
- Simple carbohydrates+0.8no signal · 15%
- Alcohol-0.3no signal · 15%
- Dietary fat load+0.1no signal · 15%
DeepGene damage signature
The metagenomic + host-DNA read-out that initializes this patient's biology and, on retest, measures whether the steering worked.
- 2 opportunists above range: Escherichia coli, Clostridioides difficile
- 2 keystone species absent
- 4 resistance genes
- Tissue recycling index 36
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
- Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
- CYP2D6 Normal metabolizerExpected exposure
- GLP1R rs6923761 AAltered receptor sensitivity
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
- HRV
- 39 ms
- Sleep
- 6.8 h
- Steps
- 7,144
- Resting HR
- 59 bpm
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.