Patient P-02375

Synthetic patientMETA-24 · Day 170 · 45–54 · F · baseline S01Steering view · 3D Open companion preview

Therapy response

Stable

Tolerance

Improving

GI state

Deteriorating

Inflammatory state

Deteriorating

Nutritional resilience

Favorable

Discontinuation risk

33%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S01
Day 111 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 111.

Primary contributors, last 14 days

GI instability+15
Inflammatory activity+11
Toxicity-10
Treatment adherence+4
Nutritional resilience-3

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

90 min

stable · +0.6 vs previous 14 d

Sleep duration

Wearable

7.9 h

stable · +0.1 vs previous 14 d

Energy level

Daily log

6.9/10

stable · +0.2 vs previous 14 d

Steps

Wearable

9,573

stable · +116 vs previous 14 d

GI burden

Companion

23.3/100

worsening · +1.1 vs previous 14 d

Adherence

Companion

82 %

stable · +1.1 vs previous 14 d

Sleep quality

Wearable

58.2/100

stable · -1.1 vs previous 14 d

Glucose, CGM daily mean

CGM

126 mg/dL

stable · -1.7 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 66 from the failing basin, 35 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.
More protein
GI -7.4 next day on high-intake days · n 23

Would not help

BR-03 Behavioural Recommendation
only 27% improved among 11 similar
Keep alcohol low
GI +5.6 next day on high-intake days · n 25
Keep ultra-processed low
GI +5.4 next day on high-intake days · n 19
Keep simple carbs low
GI +4.5 next day on high-intake days · n 18

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Protein
-7.4supporter · 95%
Alcohol
+5.6detractor · 95%
Ultra-processed food
+5.4detractor · 95%
Simple carbohydrates
+4.5detractor · 73%
Insoluble fibre
-2.4no signal · 44%
Dietary fat load
-2.1no signal · 28%
Caffeine
-1.8no signal · 26%
Histamine load
-1.3no signal · 19%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer

DNA

Fictional pharmacogenomic panel

CYP2D6 Normal metabolizer
Expected exposure
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 2.9 · butyrate capacity 50/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiNormal
Bacteroides fragilisNormal
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 40 ms
Sleep: 7.8 h
Steps: 9,483
Resting HR: 67 bpm

Daily log: GI score 23, nutritional resilience 66, adherence 82.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02285	42%	S14	AD-05	no change	39
P-02093	40%	S05	AD-05	no change	40
P-02031	36%	S12	AD-05	improved	47
P-02552	36%	S07	AD-05	no change	29
P-02522	47%	S01	BR-03	no change	40
P-02087	40%	S01	BR-03	no change	40
P-02325	39%	S19	BR-03	no change	33
P-02564	38%	S15	BR-03	improved	32
P-02439	36%	S08	BR-03	no change	40
P-02267	34%	S09	BR-03	no change	45
P-02331	34%	S14	BR-03	improved	34
P-02308	33%	S13	BR-03	no change	27