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Patient P-02469

Synthetic patientMETA-24 · Day 160 · 45–54 · F · baseline S15Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Favorable
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Favorable
Discontinuation risk
36%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 startedBaseline state S15
  2. Day 34 Trajectory diverged from predictionObserved response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 34.

Primary contributors, last 14 days
  • GI instability+15
  • Inflammatory activity+11
  • Treatment adherence+6
  • Nutritional resilience-4

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Active minutes
    Wearable
    46 min
    stable · +0.6 vs previous 14 d
    Sleep duration
    Wearable
    7.4 h
    stable · +0.2 vs previous 14 d
    Energy level
    Daily log
    5.2/10
    improving · +0.5 vs previous 14 d
    Steps
    Wearable
    4,226
    improving · +167 vs previous 14 d
    GI burden
    Companion
    25.6/100
    improving · -4.5 vs previous 14 d
    Adherence
    Companion
    90.6 %
    stable · +0.9 vs previous 14 d
    Sleep quality
    Wearable
    45.3/100
    improving · +4.9 vs previous 14 d
    Glucose, CGM daily mean
    CGM
    136 mg/dL
    stable · -0.9 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 59 from the failing basin, 50 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    • More protein
      GI -3.9 next day on high-intake days · n 19
    Would not help
    • BR-03 Behavioural Recommendation
      only 22% improved among 9 similar
    • Keep histamine low
      GI +5.3 next day on high-intake days · n 19
    • Keep ultra-processed low
      GI +4 next day on high-intake days · n 20
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Histamine load
      +5.3detractor · 95%
    • Ultra-processed food
      +4detractor · 85%
    • Protein
      -3.9supporter · 95%
    • Insoluble fibre
      -1.9no signal · 37%
    • Alcohol
      +1.4no signal · 26%
    • Caffeine
      +1.2no signal · 18%
    • Simple carbohydrates
      -0.3no signal · 15%
    • Dietary fat load
      0no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Inflammatory signalling 40
      • DNAIL6 -174 variant raises baseline inflammatory tone
      • WearableHRV 30 ms, trending down
    • Mucosal barrier integrity 30
      • DNAFUT2 non-secretor lowers mucosal fucosylation
    • Butyrate / short-chain fatty acid production 25
      • MicrobiomeF. prausnitzii depleted
    • Autonomic recovery 25
      • WearableResting HR 73 bpm
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • IL6 -174 G/C
      Higher inflammatory tone
    • CYP2D6 Intermediate metabolizer
      Expected exposure
    • GLP1R rs6923761 A
      Altered receptor sensitivity
    Microbiome
    Shannon diversity 4 · butyrate capacity 57/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisNormal
    • Bifidobacterium longumLow
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    34 ms
    Sleep
    7.5 h
    Steps
    4,271
    Resting HR
    71 bpm
    Daily log: GI score 26, nutritional resilience 62, adherence 91.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Eat slowly and stop at comfortable fullness — smaller volume, more often
    What to do
    • Log the daily check-in; one line is enough
    • A 15-minute walk after lunch
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the dose at the same time relative to your evening meal
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0255254%S07AD-05no change29
    P-0209336%S05AD-05no change40
    P-0228532%S14AD-05no change39
    P-0203130%S12AD-05improved47
    P-0256450%S15BR-03improved32
    P-0232536%S19BR-03no change33
    P-0252235%S01BR-03no change40
    P-0230833%S13BR-03no change27
    P-0208732%S01BR-03no change40
    P-0243932%S08BR-03no change40
    P-0233131%S14BR-03improved34
    P-0226728%S09BR-03no change45