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Patient P-02545

Synthetic patientMETA-24 · Day 168 · 45–54 · F · baseline S18Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Deteriorating
GI state
Favorable
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
20%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 started — Baseline state S18
  2. Day 22 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 22.

Primary contributors, last 14 days
  • Inflammatory activity+7
  • Nutritional resilience-5
  • Toxicity+5
  • GI instability+2

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Active minutes
    Wearable
    31 min
    worsening · -4.7 vs previous 14 d
    Sleep duration
    Wearable
    7.3 h
    stable · +0.1 vs previous 14 d
    Energy level
    Daily log
    5.6/10
    stable · -0.1 vs previous 14 d
    Steps
    Wearable
    3,257
    worsening · -500 vs previous 14 d
    GI burden
    Companion
    22.6/100
    improving · -0.9 vs previous 14 d
    Adherence
    Companion
    83.8 %
    stable · +3.0 vs previous 14 d
    Sleep quality
    Wearable
    57.9/100
    stable · +0.9 vs previous 14 d
    Glucose, CGM daily mean
    CGM
    125 mg/dL
    stable · +0.1 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 59 from the failing basin, 44 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    • More protein
      GI -3.5 next day on high-intake days · n 22
    Would not help
    • BR-03 Behavioural Recommendation
      only 22% improved among 9 similar
    • Keep caffeine low
      GI +3.8 next day on high-intake days · n 19
    • Keep histamine low
      GI +3 next day on high-intake days · n 22
    • Keep fibre low
      GI +2 next day on high-intake days · n 18
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Caffeine
      +3.8detractor · 95%
    • Protein
      -3.5supporter · 95%
    • Histamine load
      +3detractor · 95%
    • Insoluble fibre
      +2detractor · 61%
    • Ultra-processed food
      +1.7no signal · 51%
    • Dietary fat load
      +0.4no signal · 15%
    • Alcohol
      -0.2no signal · 15%
    • Simple carbohydrates
      +0.1no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Mucosal barrier integrity ↓60
      • DNAFUT2 non-secretor lowers mucosal fucosylation
      • MicrobiomeAkkermansia low → thinner mucus layer
    • Autonomic recovery ↓45
      • WearableResting HR 74 bpm
      • Wearable3,257 steps/day
    • Drug metabolism and exposure ↑40
      • DNACYP2D6 poor metabolizer → higher exposure
    • Inflammatory signalling ↑25
      • DNAIL6 -174 variant raises baseline inflammatory tone
    • Butyrate / short-chain fatty acid production ↓25
      • MicrobiomeF. prausnitzii depleted
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • IL6 -174 G/C
      Higher inflammatory tone
    • CYP2D6 Poor metabolizer
      Higher exposure at standard dose
    • GLP1R rs6923761 A
      Altered receptor sensitivity
    Microbiome
    Shannon diversity 3.2 · butyrate capacity 45/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisNormal
    • Bifidobacterium longumLow
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    53 ms
    Sleep
    7.4 h
    Steps
    2,852
    Resting HR
    74 bpm
    Daily log: GI score 23, nutritional resilience 63, adherence 84.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Eat slowly and stop at comfortable fullness — smaller volume, more often
    What to do
    • Log the daily check-in; one line is enough
    • A 15-minute walk after lunch
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the dose at the same time relative to your evening meal
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
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    P-0255244%S07AD-05no change29
    P-0209340%S05AD-05no change40
    P-0228533%S14AD-05no change39
    P-0203132%S12AD-05improved47
    P-0256444%S15BR-03improved32
    P-0252240%S01BR-03no change40
    P-0233138%S14BR-03improved34
    P-0232537%S19BR-03no change33
    P-0243937%S08BR-03no change40
    P-0230836%S13BR-03no change27
    P-0208734%S01BR-03no change40
    P-0226728%S09BR-03no change45