700 patients110,866 observations180 daysLIVE

Patient P-02582

Synthetic patientMETA-24 · Day 177 · 55–64 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Unstable
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
96%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 startedBaseline state S14
  2. Day 75 Trajectory diverged from predictionObserved response fell below the model's expected path.
  3. Day 80 ME-01 recommendedMonitoring Escalation ME-01
  4. Day 81 Patient acceptedStarted ME-01 in the companion
  5. Day 84 Deterioration detected before clinical escalationMonitoring Escalation ME-01

What changed?

Trajectory began diverging from predicted response on Day 75.

Primary contributors, last 14 days
  • Toxicity+9
  • Inflammatory activity+8
  • GI instability-4
  • Nutritional resilience+3

What helped?

  • Monitoring Escalation ME-01Day 80
    Result: deterioration detected before clinical escalation
LIFE OS recommendation
GI Support Protocol GI-04
92%
probability of meaningful tolerance improvement
  • 284 similar trajectories
  • 88% showed improvement
  • median effect visible after 8 days

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes
Wearable
9 min
worsening · -2.0 vs previous 14 d
Sleep duration
Wearable
6.4 h
stable · -0.0 vs previous 14 d
Energy level
Daily log
2.2/10
worsening · -0.4 vs previous 14 d
Steps
Wearable
1,624
worsening · -141 vs previous 14 d
GI burden
Companion
70.2/100
worsening · +7.7 vs previous 14 d
Adherence
Companion
44.9 %
improving · +3.0 vs previous 14 d
Sleep quality
Wearable
17.2/100
worsening · -1.3 vs previous 14 d
Glucose, CGM daily mean
CGM
146 mg/dL
stable · +3.7 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →

Heading towards failing · 21 from the failing basin, 79 from restoration.

Would help
  • GI-04 GI Support Protocol
    76% improved among 66 similar · onset 8 d · confidence 95%
  • NP-02 Dietary Support Protocol
    59% improved among 32 similar · onset 10 d · confidence 69%
  • SC-12 Supportive Compound
    69% improved among 26 similar · onset 6 d · confidence 69%
  • More protein
    GI -3.7 next day on high-intake days · n 16
Would not help
  • Keep fat low
    GI +2.6 next day on high-intake days · n 23
  • Keep alcohol low
    GI +2.4 next day on high-intake days · n 23
  • Keep ultra-processed low
    GI +2.4 next day on high-intake days · n 16
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Protein
    -3.7supporter · 95%
  • Dietary fat load
    +2.6detractor · 95%
  • Alcohol
    +2.4detractor · 89%
  • Ultra-processed food
    +2.4detractor · 85%
  • Simple carbohydrates
    -0.6no signal · 17%
  • Caffeine
    -0.4no signal · 15%
  • Histamine load
    +0.3no signal · 15%
  • Insoluble fibre
    -0.3no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Inflammatory signalling 85
    • DNAIL6 -174 variant raises baseline inflammatory tone
    • MicrobiomeBacteroides fragilis expansion
    • BloodInflammatory load index 70
    • WearableHRV 15 ms, trending down
  • Butyrate / short-chain fatty acid production 80
    • MicrobiomeButyrate capacity 22/100
    • MicrobiomeF. prausnitzii depleted
    • Daily logFibre intake low in recent food logs
  • Autonomic recovery 65
    • WearableResting HR 90 bpm
    • Wearable1,624 steps/day
    • WearableShort sleep window
  • Mucosal barrier integrity 20
    • Daily logGI symptom score 70 and rising
  • Drug metabolism and exposure 20
    • BloodToxicity index 64
DNA
Fictional pharmacogenomic panel
  • IL6 -174 G/C
    Higher inflammatory tone
  • CYP2D6 Normal metabolizer
    Expected exposure
  • MTHFR C677T
    Reduced folate turnover
Microbiome
Shannon diversity 3 · butyrate capacity 22/100
  • Akkermansia muciniphilaNormal
  • Faecalibacterium prausnitziiLow
  • Bacteroides fragilisHigh
  • Bifidobacterium longumLow
  • EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
HRV
18 ms
Sleep
6.7 h
Steps
1,779
Resting HR
89 bpm
Daily log: GI score 70, nutritional resilience 30, adherence 45.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
  • Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
  • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
  • Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
  • Track each bowel movement today: time, stool form, urgency, overnight waking
  • A 15-minute walk after lunch
  • Protect a 7.5-hour sleep window; screens off 30 minutes before
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the dose at the same time relative to your evening meal
  • Electrolyte solution, one sachet after any loose stool
  • Fictional demo item: oral nutrition supplement with lunch

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

PatientSimilarityBaselineInterventionOutcomeResponse today
P-0204816%S0277
P-0211518%S14GI-04improved75
P-0257520%S14ME-01improved73
P-0255017%S0170
P-0219216%S0569
P-0265920%S0969
P-0208316%S1369
P-0259130%S1368
P-0209016%S0468
P-0226527%S07GI-04no change67
P-0253028%S0767
P-0219416%S0367