Patient P-02610
Synthetic patientMETA-24 · Day 173 · 55–64 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Deteriorating
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
96%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S14
- Day 47 NP-02 recommended — Dietary Support Protocol NP-02
- Day 48 Patient accepted — Started NP-02 in the companion
- Day 58 No meaningful change — Dietary Support Protocol NP-02
- Day 71 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 71.
Primary contributors, last 14 days
- Inflammatory activity+8
- Toxicity+7
- Nutritional resilience-6
- GI instability-5
- Treatment adherence-5
What helped?
- Dietary Support Protocol NP-02Day 47Result: no meaningful change
LIFE OS recommendation
GI Support Protocol GI-04
92%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 86% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable41 min
stable · -0.1 vs previous 14 d
Sleep duration
Wearable6.7 h
stable · +0.1 vs previous 14 d
Energy level
Daily log2.2/10
worsening · -0.4 vs previous 14 d
Steps
Wearable5,018
stable · -135 vs previous 14 d
GI burden
Companion77.4/100
worsening · +4.4 vs previous 14 d
Adherence
Companion40.9 %
worsening · -1.8 vs previous 14 d
Sleep quality
Wearable19.1/100
stable · -0.0 vs previous 14 d
Glucose, CGM daily mean
CGM152 mg/dL
stable · +1.8 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 22 from the failing basin, 86 from restoration.
Would help
- GI-04 GI Support Protocol75% improved among 67 similar · onset 8 d · confidence 96%
- ME-01 Monitoring Escalation100% improved among 42 similar · onset 3 d · confidence 70%
- SC-12 Supportive Compound69% improved among 26 similar · onset 6 d · confidence 70%
- More proteinGI -5.1 next day on high-intake days · n 22
Would not help
- NP-02 Dietary Support Protocolalready tried, no meaningful change
- Keep histamine lowGI +6.2 next day on high-intake days · n 24
- Keep fibre lowGI +4.9 next day on high-intake days · n 13
- Keep ultra-processed lowGI +4.9 next day on high-intake days · n 19
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Histamine load+6.2detractor · 95%
- Protein-5.1supporter · 95%
- Insoluble fibre+4.9detractor · 95%
- Ultra-processed food+4.9detractor · 95%
- Simple carbohydrates+3.7detractor · 95%
- Caffeine+2.8detractor · 69%
- Alcohol-1.7no signal · 34%
- Dietary fat load+0.7no signal · 16%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓80
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 77 and rising
- Inflammatory signalling ↑60
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 74
- WearableHRV 20 ms, trending down
- Butyrate / short-chain fatty acid production ↓45
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↑25
- WearableResting HR 76 bpm
- Drug metabolism and exposure ↑20
- BloodToxicity index 53
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Normal metabolizerExpected exposure
- GLP1R rs6923761 AAltered receptor sensitivity
Microbiome
Shannon diversity 1.8 · butyrate capacity 46/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 20 ms
- Sleep
- 6.6 h
- Steps
- 4,784
- Resting HR
- 78 bpm
Daily log: GI score 77, nutritional resilience 24, adherence 41.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.