Patient P-02039
Synthetic patientMETA-24 · Day 138 · 55–64 · F · baseline S14Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Unstable
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
96%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S14
- Day 65 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 81 GI-04 recommended — GI Support Protocol GI-04
- Day 82 Patient declined — Not now
What changed?
Trajectory began diverging from predicted response on Day 65.
Primary contributors, last 14 days
- GI instability+17
- Inflammatory activity+10
- Nutritional resilience-8
- Toxicity+7
- Treatment adherence-4
What helped?
- GI Support Protocol GI-04Day 81Declined by patient
LIFE OS recommendation
GI Support Protocol GI-04
92%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 89% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable11 min
worsening · -1.4 vs previous 14 d
Sleep duration
Wearable5.4 h
improving · +0.4 vs previous 14 d
Energy level
Daily log1.6/10
worsening · -0.1 vs previous 14 d
Steps
Wearable300
stable · -13 vs previous 14 d
GI burden
Companion63.7/100
stable · +2.0 vs previous 14 d
Adherence
Companion39.8 %
worsening · -2.3 vs previous 14 d
Sleep quality
Wearable20.7/100
improving · +5.0 vs previous 14 d
Glucose, CGM daily mean
CGM152 mg/dL
stable · -1.9 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 15 from the failing basin, 75 from restoration.
Would help
- GI-04 GI Support Protocol77% improved among 65 similar · onset 8 d · confidence 92%
- ME-01 Monitoring Escalation100% improved among 42 similar · onset 3 d · confidence 69%
- NP-02 Dietary Support Protocol59% improved among 32 similar · onset 10 d · confidence 69%
- More proteinGI -5.5 next day on high-intake days · n 19
Would not help
- Keep fat lowGI +6.7 next day on high-intake days · n 18
- Keep caffeine lowGI +6.7 next day on high-intake days · n 25
- Keep histamine lowGI +6.6 next day on high-intake days · n 19
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+6.7detractor · 95%
- Caffeine+6.7detractor · 95%
- Histamine load+6.6detractor · 95%
- Protein-5.5supporter · 95%
- Simple carbohydrates+5.4detractor · 95%
- Ultra-processed food+5.2detractor · 95%
- Insoluble fibre+3detractor · 58%
- Alcohol+3detractor · 56%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓90
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 64 and rising
- WearableSleep 5.4 h, below personal baseline
- Autonomic recovery ↓65
- WearableResting HR 79 bpm
- Wearable300 steps/day
- WearableShort sleep window
- Drug metabolism and exposure ↑60
- DNACYP2D6 poor metabolizer → higher exposure
- BloodToxicity index 62
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 31/100
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↑25
- BloodInflammatory load index 66
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Poor metabolizerHigher exposure at standard dose
Microbiome
Shannon diversity 1.9 · butyrate capacity 31/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 39 ms
- Sleep
- 5.4 h
- Steps
- 463
- Resting HR
- 77 bpm
Daily log: GI score 64, nutritional resilience 37, adherence 40.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.