Patient P-02274

Synthetic patientMETA-24 · Day 138 · 75+ · F · baseline S15Steering view · 3D Open companion preview

Therapy response

Stable

Tolerance

Deteriorating

GI state

Improving

Inflammatory state

Favorable

Nutritional resilience

Favorable

Discontinuation risk

17%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S15
Day 14 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 22 DT-01 recommended — Dosing / Timing Recommendation DT-01
Day 23 Patient accepted — Started DT-01 in the companion
Day 28 GI symptom burden −22% vs expected — Dosing / Timing Recommendation DT-01
Day 34 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 14.

Primary contributors, last 14 days

GI instability-10
Toxicity+8
Inflammatory activity+4
Nutritional resilience-3
Treatment adherence-2

What helped?

Dosing / Timing Recommendation DT-01Day 22
Result: symptom burden −22%

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

31 min

worsening · -3.1 vs previous 14 d

Sleep duration

Wearable

5.6 h

stable · +0.0 vs previous 14 d

Energy level

Daily log

5.3/10

stable · +0.2 vs previous 14 d

Steps

Wearable

4,163

worsening · -306 vs previous 14 d

GI burden

Companion

21.5/100

worsening · +4.0 vs previous 14 d

Adherence

Companion

93.7 %

stable · -3.0 vs previous 14 d

Sleep quality

Wearable

24.5/100

stable · +0.0 vs previous 14 d

Glucose, CGM daily mean

CGM

139 mg/dL

stable · +1.7 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards restoration · 63 from the failing basin, 31 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.
More protein
GI -3.7 next day on high-intake days · n 18

Would not help

Keep histamine low
GI +3.9 next day on high-intake days · n 20
Keep fat low
GI +3.8 next day on high-intake days · n 18

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Histamine load
+3.9detractor · 95%
Dietary fat load
+3.8detractor · 95%
Protein
-3.7supporter · 95%
Insoluble fibre
+1no signal · 29%
Caffeine
+0.8no signal · 22%
Simple carbohydrates
+0.4no signal · 15%
Alcohol
-0.4no signal · 15%
Ultra-processed food
0no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Mucosal barrier integrity ↓70
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- WearableSleep 5.6 h, below personal baseline
Butyrate / short-chain fatty acid production ↓35
- MicrobiomeButyrate capacity 30/100
Inflammatory signalling ↑20
- MicrobiomeBacteroides fragilis expansion
Autonomic recovery ↑20
- WearableShort sleep window

DNA

Fictional pharmacogenomic panel

FUT2 rs601338 AA (non-secretor)
Reduced mucosal fucosylation
CYP2D6 Normal metabolizer
Expected exposure
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 3 · butyrate capacity 30/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 41 ms
Sleep: 6.4 h
Steps: 4,254
Resting HR: 68 bpm

Daily log: GI score 22, nutritional resilience 61, adherence 94.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
A 15-minute walk after lunch
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02285	38%	S14	AD-05	no change	39
P-02093	36%	S05	AD-05	no change	40
P-02031	35%	S12	AD-05	improved	47
P-02087	40%	S01	BR-03	no change	40
P-02267	39%	S09	BR-03	no change	45
P-02483	38%	S06	BR-03	no change	64
P-02280	36%	S07	BR-03	no change	50
P-02522	35%	S01	BR-03	no change	40
P-02564	34%	S15	BR-03	improved	32
P-02235	53%	S14	DT-01	improved	50
P-02339	50%	S03	DT-01	improved	50
P-02330	48%	S15	DT-01	no change	57