Patient P-02308

Synthetic patientMETA-24 · Day 157 · 35–44 · F · baseline S13Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Favorable

GI state

Deteriorating

Inflammatory state

Deteriorating

Nutritional resilience

Declining

Discontinuation risk

35%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S13
Day 10 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 108 BR-03 recommended — Behavioural Recommendation BR-03
Day 109 Patient accepted — Started BR-03 in the companion
Day 116 No meaningful change — Behavioural Recommendation BR-03

What changed?

Trajectory began diverging from predicted response on Day 10.

Primary contributors, last 14 days

Inflammatory activity+15
GI instability+12
Nutritional resilience-6
Treatment adherence-6
Toxicity+3

What helped?

Behavioural Recommendation BR-03Day 108
Result: no meaningful change

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

68 min

stable · +1.6 vs previous 14 d

Sleep duration

Wearable

6.9 h

stable · +0.0 vs previous 14 d

Energy level

Daily log

5.1/10

worsening · -0.2 vs previous 14 d

Steps

Wearable

6,666

worsening · -337 vs previous 14 d

GI burden

Companion

25.6/100

improving · -1.3 vs previous 14 d

Adherence

Companion

84.4 %

worsening · -4.7 vs previous 14 d

Sleep quality

Wearable

49.1/100

improving · +2.8 vs previous 14 d

Glucose, CGM daily mean

CGM

132 mg/dL

stable · -1.7 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 53 from the failing basin, 53 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.
More protein
GI -4.8 next day on high-intake days · n 21
More simple carbs
GI -2.4 next day on high-intake days · n 25

Would not help

BR-03 Behavioural Recommendation
already tried, no meaningful change

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Protein
-4.8supporter · 95%
Simple carbohydrates
-2.4supporter · 55%
Insoluble fibre
+2.4no signal · 54%
Dietary fat load
-1.1no signal · 16%
Alcohol
-1.1no signal · 26%
Histamine load
+0.5no signal · 15%
Caffeine
+0.4no signal · 15%
Ultra-processed food
-0.4no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Autonomic recovery ↓25
- WearableResting HR 77 bpm
Inflammatory signalling ↑20
- MicrobiomeBacteroides fragilis expansion

DNA

Fictional pharmacogenomic panel

CYP2D6 Intermediate metabolizer
Expected exposure
GLP1R rs6923761 A
Altered receptor sensitivity
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 3.8 · butyrate capacity 55/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumNormal
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 57 ms
Sleep: 7.2 h
Steps: 6,506
Resting HR: 74 bpm

Daily log: GI score 26, nutritional resilience 57, adherence 84.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02093	44%	S05	AD-05	no change	40
P-02285	37%	S14	AD-05	no change	39
P-02031	33%	S12	AD-05	improved	47
P-02552	32%	S07	AD-05	no change	29
P-02087	44%	S01	BR-03	no change	40
P-02522	39%	S01	BR-03	no change	40
P-02439	38%	S08	BR-03	no change	40
P-02325	35%	S19	BR-03	no change	33
P-02638	34%	S01	BR-03	improved	41
P-02564	33%	S15	BR-03	improved	32
P-02267	31%	S09	BR-03	no change	45
P-02331	31%	S14	BR-03	improved	34