Patient P-02325

Synthetic patientMETA-24 · Day 175 · 55–64 · M · baseline S19Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Improving

GI state

Favorable

Inflammatory state

Favorable

Nutritional resilience

Favorable

Discontinuation risk

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S19
Day 25 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 108 BR-03 recommended — Behavioural Recommendation BR-03
Day 109 Patient accepted — Started BR-03 in the companion
Day 116 No meaningful change — Behavioural Recommendation BR-03

What changed?

Trajectory began diverging from predicted response on Day 25.

Primary contributors, last 14 days

Toxicity-11
Treatment adherence-2

What helped?

Behavioural Recommendation BR-03Day 108
Result: no meaningful change

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

80 min

improving · +4.6 vs previous 14 d

Sleep duration

Wearable

6.8 h

stable · -0.0 vs previous 14 d

Energy level

Daily log

7.1/10

improving · +0.5 vs previous 14 d

Steps

Wearable

8,486

stable · +234 vs previous 14 d

GI burden

Companion

12.4/100

improving · -5.5 vs previous 14 d

Adherence

Companion

83.7 %

stable · -1.8 vs previous 14 d

Sleep quality

Wearable

37.2/100

improving · +2.8 vs previous 14 d

Glucose, CGM daily mean

CGM

128 mg/dL

stable · -0.5 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading drifting · 77 from the failing basin, 46 from restoration.

Good elements to keep

Butyrate producers intact
hidden · steering +7.5
Behavioural Recommendation BR-03
intervention · steering +5.2
Protein (supports)
perturbation · steering +4.8
Ultra-processed food (supports)
perturbation · steering +2.6
Protein
supporter · GI -2.8 next day
Ultra-processed food
supporter · GI -1.7 next day

Main detractors to watch

FUT2 non-secretor
hidden · steering -10.6
Rapid metabolizer
hidden · steering -8
Enterobacteriaceae elevated
hidden · steering -7.4
Antibiotic course
perturbation · steering -4.7
Histamine load
detractor · GI +2.3 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Protein
-2.8supporter · 95%
Histamine load
+2.3detractor · 83%
Ultra-processed food
-1.7supporter · 70%
Dietary fat load
+1.6no signal · 36%
Insoluble fibre
+0.7no signal · 26%
Simple carbohydrates
+0.4no signal · 15%
Alcohol
+0.3no signal · 15%
Caffeine
+0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
Autonomic recovery ↓25
- WearableResting HR 75 bpm
Inflammatory signalling ↑15
- WearableHRV 36 ms, trending down

DNA

Fictional pharmacogenomic panel

FUT2 rs601338 AA (non-secretor)
Reduced mucosal fucosylation
CYP2D6 Rapid metabolizer
Expected exposure

Microbiome

Shannon diversity 4.2 · butyrate capacity 51/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiNormal
Bacteroides fragilisNormal
Bifidobacterium longumNormal
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 34 ms
Sleep: 7.1 h
Steps: 7,341
Resting HR: 73 bpm

Daily log: GI score 12, nutritional resilience 69, adherence 84.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02093	40%	S05	AD-05	no change	40
P-02285	39%	S14	AD-05	no change	39
P-02552	39%	S07	AD-05	no change	29
P-02031	35%	S12	AD-05	improved	47
P-02439	41%	S08	BR-03	no change	40
P-02522	40%	S01	BR-03	no change	40
P-02087	35%	S01	BR-03	no change	40
P-02308	35%	S13	BR-03	no change	27
P-02331	34%	S14	BR-03	improved	34
P-02564	34%	S15	BR-03	improved	32
P-02267	31%	S09	BR-03	no change	45
P-02638	28%	S01	BR-03	improved	41