Patient P-02614
Synthetic patientMETA-24 · Day 172 · 65–74 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Unstable
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
96%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S14
- Day 72 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 72.
Primary contributors, last 14 days
- GI instability+19
- Nutritional resilience-11
- Toxicity+9
- Inflammatory activity+7
- Treatment adherence-4
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
92%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 88% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable23 min
worsening · -7.1 vs previous 14 d
Sleep duration
Wearable6.5 h
stable · -0.2 vs previous 14 d
Energy level
Daily log1.4/10
worsening · -1.2 vs previous 14 d
Steps
Wearable1,715
worsening · -891 vs previous 14 d
GI burden
Companion80.1/100
worsening · +12.2 vs previous 14 d
Adherence
Companion39.7 %
stable · -0.3 vs previous 14 d
Sleep quality
Wearable34.6/100
worsening · -6.1 vs previous 14 d
Glucose, CGM daily mean
CGM153 mg/dL
stable · +4.1 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 20 from the failing basin, 87 from restoration.
Would help
- GI-04 GI Support Protocol75% improved among 65 similar · onset 8 d · confidence 97%
- ME-01 Monitoring Escalation100% improved among 42 similar · onset 3 d · confidence 74%
- NP-02 Dietary Support Protocol59% improved among 32 similar · onset 10 d · confidence 74%
- More proteinGI -4.5 next day on high-intake days · n 21
Would not help
- Keep histamine lowGI +4.2 next day on high-intake days · n 20
- Keep fat lowGI +3.5 next day on high-intake days · n 18
- Keep simple carbs lowGI +3.3 next day on high-intake days · n 20
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-4.5supporter · 95%
- Histamine load+4.2detractor · 95%
- Dietary fat load+3.5detractor · 87%
- Simple carbohydrates+3.3detractor · 95%
- Ultra-processed food+3.3detractor · 95%
- Insoluble fibre+2.8detractor · 69%
- Alcohol-1.1no signal · 25%
- Caffeine+0.3no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓80
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 80 and rising
- Inflammatory signalling ↑50
- DNAIL6 -174 variant raises baseline inflammatory tone
- BloodInflammatory load index 68
- Butyrate / short-chain fatty acid production ↓45
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↓45
- WearableResting HR 91 bpm
- Wearable1,715 steps/day
- Drug metabolism and exposure ↑20
- BloodToxicity index 58
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
- GLP1R rs6923761 AAltered receptor sensitivity
Microbiome
Shannon diversity 2.7 · butyrate capacity 48/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 40 ms
- Sleep
- 6.7 h
- Steps
- 2,498
- Resting HR
- 89 bpm
Daily log: GI score 80, nutritional resilience 28, adherence 40.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.