700 patients110,866 observations180 daysLIVE

180 trajectories in Strong responders

Trajectories

Synthetic demo data

All Strong responders · 180 Moderate responders · 160 Non-responders · 70 Early toxicity · 84 Late toxicity · 42 Delayed loss of response · 49 Resilient responder · 25 High response / high intolerance · 90

Mean lived trajectory vs baseline model

days with fewer than 10 patients are cut

solid = observed · dashed = predicted

Individual trajectories, highest risk first

P-02466D173 · risk 56%

DecliningDeterioratingresp 79

P-02541D179 · risk 30%

FavorableDeterioratingresp 82

P-02015D93 · risk 24%

DecliningImprovingresp 78

P-02507D172 · risk 21%

ImprovingDeterioratingresp 88

P-02640D174 · risk 17%

ImprovingFavorableresp 96

P-02380D100 · risk 14%

FavorableImprovingresp 74

P-02487D159 · risk 12%

ImprovingDeterioratingresp 82

P-02231D125 · risk 10%

DecliningImprovingresp 71

P-02400D127 · risk 9%

FavorableImprovingresp 73

P-02558D104 · risk 8%

ImprovingImprovingresp 80

P-02277D168 · risk 6%

ImprovingImprovingresp 92

P-02047D156 · risk 3%

FavorableFavorableresp 84