600 patients66,869 observations120 daysLIVE

32 trajectories in Resilient responder

Trajectories

Synthetic demo data

All Strong responders · 132 Moderate responders · 102 Non-responders · 54 Early toxicity · 36 Late toxicity · 30 Delayed loss of response · 30 Resilient responder · 32 High response / high intolerance · 184

Mean lived trajectory vs baseline model

days with fewer than 10 patients are cut

solid = observed · dashed = predicted

Individual trajectories, highest risk first

P-01503D111 · risk 51%

FavorableDeterioratingresp 80

P-01726D115 · risk 27%

ImprovingDeterioratingresp 86

P-01453D115 · risk 24%

DecliningDeterioratingresp 70

P-01896D114 · risk 23%

DecliningDeterioratingresp 75

P-01677D116 · risk 21%

ImprovingDeterioratingresp 86

P-01855D119 · risk 19%

DecliningDeterioratingresp 73

P-01662D115 · risk 18%

ImprovingFavorableresp 91

P-01471D111 · risk 16%

DecliningImprovingresp 79

P-01419D92 · risk 15%

FavorableFavorableresp 86

P-01749D103 · risk 15%

DecliningImprovingresp 66

P-01784D120 · risk 14%

ImprovingFavorableresp 84

P-01460D110 · risk 11%

ImprovingImprovingresp 82