600 patients66,869 observations120 daysLIVE

184 trajectories in High response / high intolerance

Trajectories

Synthetic demo data

All Strong responders · 132 Moderate responders · 102 Non-responders · 54 Early toxicity · 36 Late toxicity · 30 Delayed loss of response · 30 Resilient responder · 32 High response / high intolerance · 184

Mean lived trajectory vs baseline model

days with fewer than 10 patients are cut

solid = observed · dashed = predicted

Individual trajectories, highest risk first

P-01332D102 · risk 96%

StableUnstableresp 43

P-01762D117 · risk 96%

UnstableUnstableresp 40

P-01865D111 · risk 96%

ImprovingUnstableresp 51

P-01328D102 · risk 92%

StableUnstableresp 49

P-01891D97 · risk 88%

UnstableImprovingresp 41

P-01582D117 · risk 83%

DecliningUnstableresp 45

P-01360D93 · risk 78%

ImprovingUnstableresp 52

P-01403D98 · risk 73%

ImprovingDeterioratingresp 49

P-01595D103 · risk 69%

StableImprovingresp 51

P-01709D113 · risk 64%

DecliningStableresp 43

P-01501D101 · risk 59%

StableImprovingresp 45

P-01529D98 · risk 54%

DecliningStableresp 44