600 patients66,869 observations120 daysLIVE

132 trajectories in Strong responders

Trajectories

Synthetic demo data

All Strong responders · 132 Moderate responders · 102 Non-responders · 54 Early toxicity · 36 Late toxicity · 30 Delayed loss of response · 30 Resilient responder · 32 High response / high intolerance · 184

Mean lived trajectory vs baseline model

days with fewer than 10 patients are cut

solid = observed · dashed = predicted

Individual trajectories, highest risk first

P-01353D114 · risk 44%

DecliningDeterioratingresp 75

P-01420D109 · risk 31%

FavorableDeterioratingresp 85

P-01608D119 · risk 23%

FavorableDeterioratingresp 79

P-01763D117 · risk 19%

ImprovingDeterioratingresp 100

P-01395D114 · risk 15%

DecliningImprovingresp 77

P-01637D112 · risk 14%

FavorableImprovingresp 85

P-01665D115 · risk 12%

ImprovingImprovingresp 83

P-01738D101 · risk 11%

ImprovingFavorableresp 87

P-01766D118 · risk 10%

ImprovingImprovingresp 90

P-01495D104 · risk 8%

FavorableImprovingresp 85

P-01852D114 · risk 7%

FavorableFavorableresp 86

P-01654D116 · risk 4%

FavorableImprovingresp 85