Patient P-03322
Immune response 62 at the day-84 endpoint (observed).
Responding: response probability 65%, immune response 69 today; biology is not blocking the drug.
No side effect starting: immune-related gi adverse events 26, immune-related toxicity 21, no drift from the model.
5 of 5 scheduled doses in the last 60 days are biologically confirmed (100%). Dose signature: resting HR +6 bpm, HRV −9 ms.
Trajectory is stable relative to similar patients; keep the current content.
- 🍽Keep meals regular; three to four moderate portions spaced through the day
- 🍽Include a cooked vegetable portion with each main meal
- ✓Log the daily check-in; one line is enough
- ✓Keep the current walking rhythm
- 💊Take the scheduled dose as agreed with your care team
- 💊No additional supplements this week
Adherence is not the problem.
sleep quality falling under 35 while GI rises
P-03322 is on day 142 of ONX-7 (MR, baseline S10): response improving, tolerance deteriorating, GI favorable. Over 14 days response moved +13 and GI -2; discontinuation risk is 18%. The state is in the restoration basin, heading towards restoration.
Butyrate capacity 54/100, diversity 3.2, normal metabolizer. Pushing it down: Escherichia coli 11.003% (LPS load) (-32.5), Enterobacteriaceae elevated (-14), H2S production above band (-12.5). Pulling it up: Butyrate producers intact (+14.2), Protein (supports) (+6.8). From the daily log: protein -1.6 GI next day, lactose +1.4 GI next day.
No action has been tried yet.
No action is indicated now; the trajectory is stable relative to similar patients.
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and events- Day 0 ONX-7 started — Baseline state S10
What changed?
Trajectory is tracking the baseline prediction.
- Inflammatory activity-6
- Toxicity+6
- Treatment adherence+5
- GI instability-2
- Nutritional resilience-2
What helped?
No interventions yet.
Daily trackers
Asset settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Heading towards restoration · 73 from the failing basin, 14 from restoration.
- No untried action with strong evidence. Compose one from primitives.
- More proteinGI -1.6 next day on high-intake days · n 18
- Keep lactose lowGI +1.4 next day on high-intake days · n 14
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-1.6supporter · 72%
- Lactose+1.4detractor · 60%
- Histamine load-1no signal · 40%
- Dietary fat load+0.9no signal · 36%
- Caffeine-0.9no signal · 35%
- Alcohol-0.5no signal · 17%
DeepGene damage signature
The metagenomic + host-DNA read-out that initializes this patient's biology and, on retest, measures whether the steering worked.
- 3 opportunists above range: Escherichia coli, Klebsiella pneumoniae, Streptococcus gallolyticus
- 2 keystone species absent
- 4 resistance genes
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
- Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
- Autonomic recovery ↓20
- WearableShort sleep window
- Inflammatory signalling ↓15
- WearableHRV 22 ms, trending down
- Mucosal barrier integrity ↓10
- WearableSleep 6.1 h, below personal baseline
- CYP2D6 Normal metabolizerExpected exposure
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
- HRV
- 27 ms
- Sleep
- 5.9 h
- Steps
- 6,661
- Resting HR
- 59 bpm
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-03264 | 35% | S17 | AD-05 | improved | 51 |
| P-03358 | 29% | S06 | AD-05 | improved | 51 |
| P-03029 | 26% | S19 | AD-05 | no change | 42 |
| P-03108 | 40% | S01 | BR-03 | no change | 60 |
| P-03181 | 36% | S11 | BR-03 | improved | 65 |
| P-03228 | 32% | S20 | BR-03 | no change | 68 |
| P-03213 | 29% | S16 | BR-03 | improved | 47 |
| P-03418 | 29% | S18 | BR-03 | improved | 40 |
| P-03462 | 29% | S20 | BR-03 | improved | 77 |
| P-03117 | 28% | S10 | BR-03 | improved | 37 |
| P-03207 | 28% | S16 | CR-01 | improved | 72 |
| P-03001 | 27% | S14 | CR-01 | improved | 53 |